AutismKB 2.0

Annotation Detail for PER1


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Basic Information Top
Gene Symbol:PER1 ( MGC88021,PER,RIGUI,hPER )
Gene Full Name: period homolog 1 (Drosophila)
Band: 17p13.1
Quick LinksEntrez ID:5187; OMIM: 602260; Uniprot ID:PER1_HUMAN; ENSEMBL ID: ENSG00000179094; HGNC ID: 8845
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
498Nuclear export signal (By similarity).
704Phosphoserine.
815Phosphoserine.
843Nuclear localization signal (By
979Phosphoserine.
980Phosphoserine.
1100Phosphoserine.
1103Phosphoserine.
1104Phosphoserine.
1262Phosphoserine.
1263Phosphoserine.
Location(AA) Modifications Resource
979Phosphoserine.Swiss-Prot 53.0
979PhosphoserinePhospho.ELM 6.0
980Phosphoserine.Swiss-Prot 53.0
980PhosphoserinePhospho.ELM 6.0
1100Phosphoserine.Swiss-Prot 53.0
1103Phosphoserine.Swiss-Prot 53.0
1104Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
27O-linkedHMM predict
27Phosphoserine(CDC2)HMM predict
27Phosphoserine(CDK)HMM predict
50N-linkedHMM predict
53Phosphoserine(ATM)HMM predict
55N-linkedHMM predict
66Phosphoserine(ATM)HMM predict
66Phosphoserine(IKK)HMM predict
70O-linkedHMM predict
73Phosphoserine(CK1)HMM predict
74Phosphoserine(CK1)HMM predict
75Phosphoserine(CK1)HMM predict
92Phosphoserine(CK1)HMM predict
92Phosphoserine(IKK)HMM predict
93O-linkedHMM predict
95Phosphoserine(ATM)HMM predict
95Phosphoserine(IKK)HMM predict
97Phosphoserine(CDC2)HMM predict
97Phosphoserine(ATM)HMM predict
99O-linkedHMM predict
99Phosphoserine(CDC2)HMM predict
99Phosphoserine(ATM)HMM predict
99Phosphoserine(IKK)HMM predict
118N-linkedHMM predict
120O-linkedHMM predict
134Phosphothreonine(PKC)HMM predict
161Phosphothreonine(PKA)HMM predict
161Phosphothreonine(PKC)HMM predict
182SulfotyrosineHMM predict
361Phosphothreonine(PKC)HMM predict
365Phosphothreonine(PKA)HMM predict
434Phosphotyrosine(INSR)HMM predict
434Phosphotyrosine(SRC)HMM predict
434Phosphotyrosine(Jak)HMM predict
477O-linkedHMM predict
477Phosphoserine(CDC2)HMM predict
503Phosphoserine(CDC2)HMM predict
503Phosphoserine(MAPK)HMM predict
505O-linkedHMM predict
505Phosphoserine(CDC2)HMM predict
505Phosphoserine(MAPK)HMM predict
505Phosphoserine(CDK)HMM predict
517O-linkedHMM predict
517Phosphoserine(MAPK)HMM predict
523Phosphoserine(MAPK)HMM predict
523Phosphoserine(ATM)HMM predict
528O-linkedHMM predict
530Phosphoserine(IKK)HMM predict
573PhosphoserineHMM predict
592Phosphoserine(CDK)HMM predict
656O-linkedHMM predict
658O-linkedHMM predict
659O-linkedHMM predict
663Phosphoserine(CK2)HMM predict
687O-linkedHMM predict
692Phosphothreonine(CDC2)HMM predict
692Phosphothreonine(MAPK)HMM predict
704Phosphoserine(MAPK)HMM predict
717Phosphoserine(CK1)HMM predict
757O-linkedHMM predict
757Phosphoserine(CDC2)HMM predict
757Phosphoserine(ATM)HMM predict
757PhosphoserineHMM predict
761Phosphoserine(CDC2)HMM predict
761Phosphoserine(CDK)HMM predict
763O-linkedHMM predict
763O-linkedHMM predict
763O-linkedHMM predict
860O-linkedHMM predict
860O-linkedHMM predict
860Phosphoserine(CDC2)HMM predict
860Phosphoserine(CDK)HMM predict
865O-linkedHMM predict
866O-linkedHMM predict
866O-linkedHMM predict
866O-linkedHMM predict
866Phosphothreonine(MAPK)HMM predict
870O-linkedHMM predict
870Phosphothreonine(MAPK)HMM predict
874O-linkedHMM predict
875O-linkedHMM predict
890Phosphoserine(CDC2)HMM predict
903O-linkedHMM predict
904O-linkedHMM predict
941Phosphothreonine(MAPK)HMM predict
948O-linkedHMM predict
948Phosphothreonine(MAPK)HMM predict
951O-linkedHMM predict
953O-linkedHMM predict
953Phosphoserine(CDK)HMM predict
953Phosphoserine(IKK)HMM predict
955O-linkedHMM predict
955Phosphoserine(IKK)HMM predict
957O-linkedHMM predict
964Phosphoserine(CDC2)HMM predict
964Phosphoserine(ATM)HMM predict
980Phosphoserine(CDC2)HMM predict
980Phosphoserine(IKK)HMM predict
1006O-linkedHMM predict
1007O-linkedHMM predict
1014O-linkedHMM predict
1014O-linkedHMM predict
1037Phosphoserine(CK1)HMM predict
1037Phosphoserine(CK2)HMM predict
1037Phosphoserine(ATM)HMM predict
1053Phosphoserine(CK1)HMM predict
1053Phosphoserine(IKK)HMM predict
1084O-linkedHMM predict
1086O-linkedHMM predict
1094O-linkedHMM predict
1112MethylarginineHMM predict
1207Phosphoserine(CK1)HMM predict
1263Phosphoserine(ATM)HMM predict
1277Phosphoserine(PKG)HMM predict
1278O-linkedHMM predict
1278Phosphoserine(PKA)HMM predict
1279O-linkedHMM predict
1279Phosphoserine(CDC2)HMM predict
1279Phosphoserine(CDK)HMM predict
1279Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002616
  • Location:chr17 7984514-7996426
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 7999077 8000375 1298 3300
H3K4me3 colorectalcancer 7999077 8000300 1223 3262
H3ac HepG2E 7996856 7998241 1385 1122
H3ac HepG2E 7998950 8000264 1314 3181
Oct1 H2O2-HelaGSE14283 7996845 7996878 33 435
Oct1 HelaGSE14283 7996846 7996878 32 436
USF1 HepG2E 7996633 7998277 1644 1029
USF1 HepG2E 7999035 8000300 1265 3241
USF2 HepG2E 7996822 7998241 1419 1105
USF2 HepG2E 7999035 8000264 1229 3223
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 7982399 7983176 777 1727
KLF4 hESGSE17917 7982984 7983204 220 1421
Myc hESGSE17917 7977563 7977799 236 6834
Pol3 GM12878GSE19551 7982620 7983954 1334 1228
RARA MCF7GSE15244 7982470 7983824 1354 1368
RARG MCF7GSE15244 7982364 7982830 466 1918
Rb GrowingGSE19898 7982691 7983017 326 1661
Rb QuiescentGSE19898 7982729 7983018 289 1641
Rb SenescentGSE19898 7982599 7983252 653 1589
Rb shRbQuiescentGSE19898 7982679 7982930 251 1710
Rb shRbSenescenceGSE19898 7982785 7982936 151 1654
Rb shRbSenescenceGSE19898 7983165 7983421 256 1222
TAF k562GSE8489 7981431 7982057 626 2771
TAF k562GSE8489 7982364 7983014 650 1826
hScc1 BcellGSE12603 7982585 7983249 664 1598
hScc1 CdLSGSE12603 7982364 7983390 1026 1638
p130 QuiescentGSE19898 7982737 7983064 327 1614
p130 SenescentGSE19898 7982665 7983403 738 1481
p130 shRbQuiescentGSE19898 7982361 7983285 924 1692
p130 shRbSenescentGSE19898 7982599 7983131 532 1650
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 7994881 7997030 2149 0
ETS1 JurkatGSE17954 7994908 7995889 981 0
Oct1 HelaGSE14283 7991135 7991170 35 0
TFAP2C MCF7GSE21234 7994880 7995525 645 0
hScc1 BcellGSE12603 7985178 7985419 241 0
hScc1 BcellGSE12603 7986013 7986861 848 0
hScc1 BcellGSE12603 7995490 7995882 392 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-181d hsa-mir-181d 19 19478556
hsa-miR-191 hsa-mir-191 3 19478556
hsa-miR-191* hsa-mir-191 3 19478556
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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