Annotation Detail for PFAS
Basic Information Top
| Gene Symbol: | PFAS ( FGAMS,FGARAT,KIAA0361,PURL ) |
|---|---|
| Gene Full Name: | phosphoribosylformylglycinamidine synthase |
| Band: | 17p13.1 |
| Quick Links | Entrez ID:5198; OMIM: 602133; Uniprot ID:PUR4_HUMAN; ENSEMBL ID: ENSG00000178921; HGNC ID: 8863 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 569 | Phosphoserine. | |
| 619 | Phosphothreonine. | |
| 623 | Phosphothreonine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 569 | Phosphoserine. | Swiss-Prot 53.0 |
| 569 | Phosphoserine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 45 | N-linked | HMM predict |
| 95 | N-linked | HMM predict |
| 100 | O-linked | HMM predict |
| 121 | Phosphothreonine(PKC) | HMM predict |
| 162 | Phosphoserine(ATM) | HMM predict |
| 165 | Phosphoserine(IKK) | HMM predict |
| 256 | Phosphoserine(CK1) | HMM predict |
| 272 | N-linked | HMM predict |
| 321 | O-linked | HMM predict |
| 475 | N-linked | HMM predict |
| 619 | Phosphothreonine(CDC2) | HMM predict |
| 619 | Phosphothreonine(MAPK) | HMM predict |
| 619 | O-linked | HMM predict |
| 619 | Phosphothreonine(CDK) | HMM predict |
| 623 | Phosphothreonine(MAPK) | HMM predict |
| 703 | Phosphothreonine(MAPK) | HMM predict |
| 816 | Phosphothreonine(PKC) | HMM predict |
| 822 | Phosphoserine(IKK) | HMM predict |
| 837 | O-linked | HMM predict |
| 839 | Phosphothreonine(MAPK) | HMM predict |
| 839 | Phosphothreonine(CDK) | HMM predict |
| 1062 | Phosphoserine(CDC2) | HMM predict |
| 1185 | Phosphoserine(ATM) | HMM predict |
| 1237 | Phosphotyrosine(EGFR) | HMM predict |
| 1265 | N-linked | HMM predict |
| 1275 | N-linked | HMM predict |
| 1277 | Phosphoserine(CDC2) | HMM predict |
| 1277 | O-linked | HMM predict |
| 1331 | N-linked | HMM predict |
- RefSeq ID: NM_012393
- Location:chr17 8093361-8114527
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| PolII | HeLa | GSE12783 | 8090880 | 8094705 | 3825 | 569 |
| p130 | Senescent | GSE19898 | 8092993 | 8093703 | 710 | 14 |
| p130 | shRbQuiescent | GSE19898 | 8092912 | 8093705 | 793 | 53 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Oct1 | H2O2-Hela | GSE14283 | 8120632 | 8120672 | 40 | 6125 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 8093409 | 8093632 | 223 | 0 |
| CTCF | G2 | GSE9613 | 8112666 | 8113017 | 351 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 8093955 | 8094692 | 737 | 0 |
| H3K4me3 | colorectal | cancer | 8093549 | 8094100 | 551 | 0 |
| H3ac | HepG2 | E | 8092912 | 8094692 | 1780 | 0 |
| LIN9 | G0 | GSE7516 | 8093215 | 8093839 | 624 | 0 |
| LIN9 | S | GSE7516 | 8093139 | 8093876 | 737 | 0 |
| RARG | MCF7 | GSE15244 | 8093409 | 8094257 | 848 | 0 |
| Rb | Quiescent | GSE19898 | 8093145 | 8093679 | 534 | 0 |
| Rb | Senescent | GSE19898 | 8093223 | 8093533 | 310 | 0 |
| TAF | Hela | GSE8489 | 8093517 | 8094692 | 1175 | 0 |
| TAF | k562 | GSE8489 | 8093517 | 8094692 | 1175 | 0 |
| VDR | GM10855-stim | GSE22484 | 8092611 | 8094286 | 1675 | 0 |
| hScc1 | Bcell | GSE12603 | 8099515 | 8099783 | 268 | 0 |
| hScc1 | Bcell | GSE12603 | 8110462 | 8110928 | 466 | 0 |
| p130 | Quiescent | GSE19898 | 8093120 | 8093644 | 524 | 0 |
| p130 | shRbSenescent | GSE19898 | 8093104 | 8093680 | 576 | 0 |
| p130 | G0 | GSE7516 | 8093215 | 8093839 | 624 | 0 |
| p130 | S | GSE7516 | 8093175 | 8093914 | 739 | 0 |
Validated miRNA targets