AutismKB 2.0

Annotation Detail for PFKP


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Basic Information Top
Gene Symbol:PFKP ( FLJ40226,PFK-C,PFKF )
Gene Full Name: phosphofructokinase, platelet
Band: 10p15.2
Quick LinksEntrez ID:5214; OMIM: 171840; Uniprot ID:K6PP_HUMAN; ENSEMBL ID: ENSG00000067057; HGNC ID: 8878
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
12Phosphoserine (By similarity).
386Phosphoserine.
395N6-acetyllysine.
486N6-acetyllysine.
651Phosphotyrosine.
688N6-acetyllysine.
783Phosphoserine.
Location(AA) Modifications Resource
386Phosphoserine.Swiss-Prot 53.0
386PhosphoserinePhospho.ELM 6.0
651Phosphotyrosine.Swiss-Prot 53.0
651PhosphotyrosinePhospho.ELM 6.0
783Phosphoserine.Swiss-Prot 53.0
783PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
84Phosphoserine(CK1)HMM predict
204O-linkedHMM predict
223Phosphotyrosine(Jak)HMM predict
242Phosphoserine(ATM)HMM predict
340Phosphothreonine(MAPK)HMM predict
393Phosphothreonine(PKC)HMM predict
475Phosphoserine(IKK)HMM predict
493Phosphothreonine(PKC)HMM predict
499Phosphoserine(IKK)HMM predict
558O-linkedHMM predict
573Phosphothreonine(PKC)HMM predict
604SulfotyrosineHMM predict
638N-linkedHMM predict
644N-linkedHMM predict
712Phosphothreonine(PKC)HMM predict
712Phosphothreonine(CK2)HMM predict
773Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002627
  • Location:chr10 3099751-3168994
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 3090134 3090487 353 9441
TFAP2C MCF7GSE21234 3086325 3086777 452 13201
hScc1 BcellGSE12603 3098858 3099543 685 551
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 3103484 3104175 691 0
FoxA1 MCF7MACSdata 3127501 3127866 365 0
Nanog hESGSE18292 3110563 3111019 456 0
PHF8 HeLaGSE20725 3099480 3101741 2261 0
PolII HeLaGSE12783 3099121 3102925 3804 0
RARA MCF7GSE15244 3124031 3124210 179 0
RARA MCF7GSE15244 3127081 3127532 451 0
RARA MCF7GSE15244 3127976 3128513 537 0
RARG MCF7GSE15244 3107521 3107731 210 0
RARG MCF7GSE15244 3126703 3127532 829 0
RARG MCF7GSE15244 3127976 3128807 831 0
RARG MCF7GSE15244 3154329 3154578 249 0
Rb GrowingGSE19898 3100980 3101206 226 0
Rb shRbSenescenceGSE19898 3155659 3155906 247 0
TFAP2C MCF7GSE21234 3154558 3155227 669 0
TFAP2C MCF7GSE21234 3158693 3159690 997 0
hScc1 BcellGSE12603 3101027 3101483 456 0
hScc1 BcellGSE12603 3116904 3117089 185 0
hScc1 BcellGSE12603 3156949 3157307 358 0
p130 SenescentGSE19898 3149712 3149881 169 0
p130 shRbSenescentGSE19898 3099751 3100065 314 0
p63 keratinocytesGSE17611 3139416 3140543 1127 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018