AutismKB 2.0

Annotation Detail for CDK14


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Basic Information Top
Gene Symbol:CDK14 ( KIAA0834,PFTAIRE1,PFTK1 )
Gene Full Name: cyclin-dependent kinase 14
Band: 7q21.13
Quick LinksEntrez ID:5218; OMIM: 610679; Uniprot ID:CDK14_HUMAN; ENSEMBL ID: ENSG00000058091; HGNC ID: 8883
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
22Phosphothreonine.
24Phosphoserine.
76Phosphothreonine.
95Phosphoserine.
119Phosphoserine.
120Phosphoserine.
122Phosphoserine.
123Phosphoserine.
134Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012395
  • Location:chr7 90176647-90677839
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 90173538 90173803 265 2977
hScc1 BcellGSE12603 90175874 90177137 1263 142
hScc1 CdLSGSE12603 90175799 90176664 865 416
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 90696541 90696588 47 18725
Oct1 HelaGSE14283 90696521 90696588 67 18715
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 90550237 90550391 154 0
CTCF CD4SISSRdata 90550237 90550391 154 0
CTCF G2GSE9613 90501840 90502063 223 0
CTCF G2GSE9613 90556481 90556783 302 0
FoxA1 MCF7MACSdata 90188284 90188507 223 0
FoxA1 MCF7MACSdata 90437671 90437784 113 0
FoxA1 MCF7MACSdata 90610024 90610341 317 0
GABP k562GSE8489 90285347 90285755 408 0
Nanog ESGSE20650 90419876 90420232 356 0
Nanog ESGSE20650 90433685 90433893 208 0
Nanog ESGSE20650 90636943 90637506 563 0
Nanog hESGSE18292 90231927 90232454 527 0
Nanog hESGSE18292 90637004 90637631 627 0
Oct1 H2O2-HelaGSE14283 90317169 90317213 44 0
Oct1 H2O2-HelaGSE14283 90326290 90326327 37 0
Oct1 H2O2-HelaGSE14283 90555412 90555476 64 0
Oct1 HelaGSE14283 90251615 90251692 77 0
Oct1 HelaGSE14283 90317169 90317213 44 0
Oct1 HelaGSE14283 90326290 90326327 37 0
Oct1 HelaGSE14283 90368275 90368322 47 0
Oct1 HelaGSE14283 90431553 90431611 58 0
Oct1 HelaGSE14283 90436728 90436769 41 0
Oct1 HelaGSE14283 90449293 90449332 39 0
Oct1 HelaGSE14283 90482640 90482680 40 0
Oct1 HelaGSE14283 90486916 90486944 28 0
Oct1 HelaGSE14283 90487239 90487287 48 0
PAX3-FKHR Rh4GSE19063 90454644 90457364 2720 0
Stat6 IL-4-hr4GSE17850 90449271 90449717 446 0
TFAP2C MCF7GSE21234 90305809 90306137 328 0
TFAP2C MCF7GSE21234 90441022 90441314 292 0
hScc1 BcellGSE12603 90501689 90502265 576 0
hScc1 BcellGSE12603 90556555 90556976 421 0
hScc1 CdLSGSE12603 90501689 90502265 576 0
hScc1 CdLSGSE12603 90556555 90557070 515 0
hScc1 G2GSE9613 90501732 90502108 376 0
Validated miRNA targets Top
No data
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
174 Unknown MicroArray miR-1 PFTK1 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000058091 "cardiac and skeletal muscles, cardiogenesis" n_a n_a "lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24292 mRNA PFTK1 chr7 89983362 90484555 623 EST chr7 90010319 90010942 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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