AutismKB 2.0

Annotation Detail for PGD


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Basic Information Top
Gene Symbol:PGD ( 6PGD )
Gene Full Name: phosphogluconate dehydrogenase
Band: 1p36.22
Quick LinksEntrez ID:5226; OMIM: 172200; Uniprot ID:6PGD_HUMAN; ENSEMBL ID: ENSG00000142657; HGNC ID: 8891
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
38N6-acetyllysine.
59N6-acetyllysine.
76N6-acetyllysine.
154N6-acetyllysine.
309N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
33N-linkedHMM predict
106Phosphotyrosine(EGFR)HMM predict
106Phosphotyrosine(Syk)HMM predict
192Phosphotyrosine(INSR)HMM predict
192SulfotyrosineHMM predict
224N-linkedHMM predict
301Phosphoserine(PKC)HMM predict
411Phosphoserine(PKG)HMM predict
468N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002631
  • Location:chr1 10381671-10402786
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 10380606 10382398 1792 170
Fos K562GSE19551 10381109 10382004 895 115
Myc hESGSE17917 10381235 10381459 224 325
Rb SenescentGSE19898 10381006 10381609 603 364
p130 SenescentGSE19898 10381100 10381918 818 163
p130 shRbSenescentGSE19898 10381088 10382059 971 98
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 10406679 10407149 470 4128
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 10381305 10382147 842 0
CTCF G2GSE9613 10395605 10395753 148 0
H3ac HepG2E 10382226 10383425 1199 0
Myc K562GSE19551 10397888 10398372 484 0
Oct1 H2O2-HelaGSE14283 10398528 10398561 33 0
Oct1 HelaGSE14283 10398528 10398562 34 0
P300 T0-glioblastomaGSE21026 10397733 10398658 925 0
P300 T30-glioblastomaGSE21026 10397801 10398806 1005 0
PHF8 HeLaGSE20725 10381015 10382774 1759 0
TAF k562GSE8489 10382369 10383425 1056 0
p130 QuiescentGSE19898 10382200 10382427 227 0
p130 SenescentGSE19898 10382111 10382425 314 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018