Annotation Detail for PGM1

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Basic Information Top

Gene Symbol:	PGM1 ( GSD14 )
Gene Full Name:	phosphoglucomutase 1
Band:	1p31.3
Quick Links	Entrez ID:5236; OMIM: 171900; Uniprot ID:PGM1_HUMAN; ENSEMBL ID: ENSG00000079739; HGNC ID: 8905
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modifications	Resource
115	Phosphothreonine (By similarity).	Swiss-Prot 53.0
117	Phosphoserine (By similarity).	Swiss-Prot 53.0
466	Phosphothreonine (PAK1)	Phospho.ELM 6.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	MCF7	E	63830023	63830272	249	1387
H3K4me3	colorectal	cancer	63830623	63831509	886	469
H3ac	HepG2	E	63830735	63831418	683	458
Oct1	H2O2-Hela	GSE14283	63827564	63827610	46	3948
Oct1	Hela	GSE14283	63827565	63827610	45	3947

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	T30-glioblastoma	GSE21026	63912400	63913105	705	14251
CTCF	Hela	GSE12889	63912631	63912974	343	14301
CTCF	G2	GSE9613	63912562	63913148	586	14354
Fos	K562	GSE19551	63912624	63912963	339	14292
Jun	K562	GSE19551	63912668	63912968	300	14317
Nanog	hES	GSE18292	63904276	63904546	270	5910
Sox2	hES	GSE18292	63904225	63904466	241	5844
hScc1	Bcell	GSE12603	63907662	63907902	240	9281
hScc1	Bcell	GSE12603	63912825	63913008	183	14415
hScc1	G2	GSE9613	63912562	63913500	938	14530

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	63854103	63854497	394
CTCF	CD4	SISSRdata	63854103	63854497	394
CTCF	G2	GSE9613	63831570	63832168	598
ER	Fulvestrant-MCF7	GSE14664	63848824	63848858	34
Nanog	hES	GSE18292	63854232	63854444	212
Oct1	H2O2-Hela	GSE14283	63839914	63839940	26
Oct1	Hela	GSE14283	63875293	63875371	78
Stat6	IL-4-hr1	GSE17850	63889316	63889995	679
hScc1	Bcell	GSE12603	63831509	63832600	1091
hScc1	CdLS	GSE12603	63854206	63854805	599

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
320	Unknown	MicroArray	miR-124	PGM1	n_a	15685193
1262	Unknown	pSILAC	miR-30	PGM1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000079739		G1-to-S transition	n_a	n_a	"epithelium, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000079739		n_a	n_a	n_a	"epithelium, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
903	mRNA	PGM1	chr1	63770967	63837935	197	EST		chr1	63667794	63771413	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018