AutismKB 2.0

Annotation Detail for PHB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PHB ( PHB1 )
Gene Full Name: prohibitin
Band: 17q21.33
Quick LinksEntrez ID:5245; OMIM: 176705; Uniprot ID:PHB_HUMAN; ENSEMBL ID: ENSG00000167085; HGNC ID: 8912
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
202N6-acetyllysine.
249Phosphotyrosine (By similarity).
252Phosphoserine.
254Phosphoserine.
265Phosphoserine.
Location(AA) Modifications Resource
252Phosphoserine.Swiss-Prot 53.0
252PhosphoserinePhospho.ELM 6.0
254Phosphoserine.Swiss-Prot 53.0
254PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
89N-linkedHMM predict
151Phosphoserine(PKA)HMM predict
151Phosphoserine(CAMK2)HMM predict
256N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002634
  • Location:chr17 44836418-44847240
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44864167 44864470 303 17078
ETS1 JurkatGSE17954 44846686 44848117 1431 161
Fos K562GSE19551 44846999 44847650 651 84
GABP k562GSE8489 44856701 44857264 563 9742
Myc K562GSE19551 44846795 44847773 978 44
P300 T0-glioblastomaGSE21026 44846771 44847963 1192 127
P300 T30-glioblastomaGSE21026 44846766 44847970 1204 128
PHF8 293TGSE20725 44846708 44848063 1355 145
RARA MCF7GSE15244 44847271 44847751 480 271
TAF k562GSE8489 44856773 44857264 491 9778
USF1 HepG2E 44847412 44847751 339 341
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 44833806 44837929 4123 551
CTCF CD4GSE12889 44827383 44827691 308 8882
CTCF CD4SISSRdata 44827383 44827691 308 8882
CTCF HelaGSE12889 44827493 44827729 236 8808
CTCF JurkatGSE12889 44827399 44827716 317 8861
CTCF G2GSE9613 44823020 44823172 152 13323
CTCF G2GSE9613 44827174 44827652 478 9006
ER Fulvestrant-MCF7GSE14664 44824156 44824205 49 12238
Oct1 HelaGSE14283 44824158 44824196 38 12242
RARA MCF7GSE15244 44827174 44827652 478 9006
RARG MCF7GSE15244 44827174 44827652 478 9006
hScc1 BcellGSE12603 44827246 44827652 406 8970
hScc1 CdLSGSE12603 44827174 44827652 478 9006
hScc1 G2GSE9613 44827174 44827652 478 9006
p130 SenescentGSE19898 44822389 44822745 356 13852
p130 SenescentGSE19898 44823050 44823265 215 13261
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 44840195 44840642 447 0
CTCF CD4SISSRdata 44840195 44840642 447 0
CTCF G2GSE9613 44840188 44840725 537 0
CTCF G2GSE9613 44846953 44847271 318 0
H3K4me3 colorectalcancer 44846422 44846953 531 0
H3ac HepG2E 44843911 44845822 1911 0
H3ac HepG2E 44846359 44847751 1392 0
Oct1 HelaGSE14283 44842876 44842906 30 0
Oct1 HelaGSE14283 44843376 44843407 31 0
hScc1 BcellGSE12603 44840225 44840900 675 0
hScc1 BcellGSE12603 44846922 44847199 277 0
hScc1 CdLSGSE12603 44840225 44840900 675 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-27a hsa-mir-27a 19 18789835
hsa-miR-27a* hsa-mir-27a 19 18789835
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved