AutismKB 2.0

Annotation Detail for PI4KA


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Basic Information Top
Gene Symbol:PI4KA ( FLJ16556,PI4K-ALPHA,PIK4CA,pi4K230 )
Gene Full Name: phosphatidylinositol 4-kinase, catalytic, alpha
Band: 22q11.21
Quick LinksEntrez ID:5297; OMIM: 600286; Uniprot ID:PI4KA_HUMAN; ENSEMBL ID: ENSG00000100038,ENSG00000241973; HGNC ID: 8983
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
172Phosphoserine.
197Phosphothreonine.
198Phosphoserine.
199Phosphoserine.
202Phosphoserine.
204Phosphoserine.
207Phosphoserine.
1096Phosphotyrosine.
1378Phosphoserine.
1770Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
86Phosphotyrosine(Syk)HMM predict
90Phosphoserine(PKB)HMM predict
90PhosphoserineHMM predict
120Phosphotyrosine(Jak)HMM predict
120Phosphotyrosine(Jak)HMM predict
139Phosphotyrosine(INSR)HMM predict
172Phosphoserine(PKA)HMM predict
197Phosphothreonine(PKA)HMM predict
198Phosphoserine(PKG)HMM predict
198Phosphoserine(IKK)HMM predict
202O-linkedHMM predict
202Phosphoserine(CK1)HMM predict
204Phosphoserine(ATM)HMM predict
216O-linkedHMM predict
217Phosphoserine(CDC2)HMM predict
217O-linkedHMM predict
248O-linkedHMM predict
249O-linkedHMM predict
253Phosphoserine(CDC2)HMM predict
308SulfotyrosineHMM predict
352Phosphoserine(ATM)HMM predict
410Phosphoserine(IKK)HMM predict
446Phosphothreonine(MAPK)HMM predict
446Phosphothreonine(CDK)HMM predict
470Phosphotyrosine(Syk)HMM predict
499Phosphoserine(ATM)HMM predict
499Phosphoserine(PKG)HMM predict
499Phosphoserine(IKK)HMM predict
504Phosphotyrosine(EGFR)HMM predict
544Phosphoserine(ATM)HMM predict
629Phosphoserine(PKG)HMM predict
633Phosphotyrosine(Jak)HMM predict
639Phosphotyrosine(Syk)HMM predict
690Phosphoserine(CAMK2)HMM predict
772Phosphoserine(IKK)HMM predict
795N-linkedHMM predict
973Phosphotyrosine(Syk)HMM predict
974Phosphotyrosine(Syk)HMM predict
974SulfotyrosineHMM predict
994Phosphoserine(PKG)HMM predict
1037Phosphoserine(ATM)HMM predict
1059N-linkedHMM predict
1225Phosphoserine(ATM)HMM predict
1238SulfotyrosineHMM predict
1271Phosphoserine(CK1)HMM predict
1309N-linkedHMM predict
1314N-linkedHMM predict
1427Phosphotyrosine(Jak)HMM predict
1432Phosphothreonine(PKA)HMM predict
1567O-linkedHMM predict
1570Phosphotyrosine(EGFR)HMM predict
1610Phosphotyrosine(INSR)HMM predict
1638Phosphotyrosine(Syk)HMM predict
1666Phosphoserine(ATM)HMM predict
1673Phosphotyrosine(EGFR)HMM predict
1768Phosphoserine(CK1)HMM predict
1866SulfotyrosineHMM predict
2006N-linkedHMM predict
2008Phosphothreonine(PKC)HMM predict
2027N-linkedHMM predict
2028ArginineHMM predict
2031Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002650
  • Location:chr22 19391990-19418954
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 19392266 19392795 529 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17174 mRNA SERPIND1 chr22 19452940 19466562 13622 mRNA PIK4CA chr22 19386544 19517555 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018