AutismKB 2.0

Annotation Detail for ACP2


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Basic Information Top
Gene Symbol:ACP2 ( - )
Gene Full Name: acid phosphatase 2, lysosomal
Band: 11p11.2
Quick LinksEntrez ID:53; OMIM: 171650; Uniprot ID:PPAL_HUMAN; ENSEMBL ID: ENSG00000134575; HGNC ID: 123
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
92N-linked (GlcNAc...).
133N-linked (GlcNAc...).
167N-linked (GlcNAc...).
177N-linked (GlcNAc...).
191N-linked (GlcNAc...) (Probable).
267N-linked (GlcNAc...).
322N-linked (GlcNAc...) (Probable).
331N-linked (GlcNAc...).
Location(AA) Modifications Resource
92N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
133N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
167N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
177N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
191N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
267N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
322N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
331N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphoserine(PKB)HMM predict
56Phosphotyrosine(Syk)HMM predict
92N-linkedHMM predict
133N-linkedHMM predict
167N-linkedHMM predict
172Phosphothreonine(MAPK)HMM predict
177N-linkedHMM predict
182N-linkedHMM predict
191N-linkedHMM predict
267N-linkedHMM predict
275Phosphoserine(ATM)HMM predict
345S-palmitoylHMM predict
413TyrosineHMM predict
414ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001610
  • Location:chr11 47217428-47226938
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 47226431 47227716 1285 135
FOXA1 MCF7GSE15244 47226936 47227912 976 486
GABP HelaGSE8489 47226936 47227807 871 433
GABP k562GSE8489 47228572 47228861 289 1778
GATA3 MCF7GSE15244 47226936 47227323 387 191
H3ac HepG2E 47227151 47227912 761 593
H3ac HepG2E 47228572 47228861 289 1778
P300 T0-glioblastomaGSE21026 47226402 47227650 1248 88
P300 T30-glioblastomaGSE21026 47226463 47227715 1252 151
PHF8 293TGSE20725 47226550 47227669 1119 171
PHF8 HeLaGSE20725 47226316 47227838 1522 139
PHF8 Hs68plusFBSGSE20725 47226315 47227933 1618 186
RARG MCF7GSE15244 47227005 47227356 351 242
Rb QuiescentGSE19898 47226734 47227153 419 5
TAFII hESGSE17917 47226593 47227399 806 58
p130 QuiescentGSE19898 47226752 47227272 520 74
p130 SenescentGSE19898 47226613 47227739 1126 238
p130 shRbQuiescentGSE19898 47226436 47227617 1181 88
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 47221052 47221940 888 0
FOXA1 MCF7GSE15244 47225845 47226402 557 0
FoxA1 MCF7MACSdata 47221539 47221902 363 0
GABP HelaGSE8489 47225881 47226651 770 0
GABP k562GSE8489 47225026 47227880 2854 0
H3K4me3 colorectalcancer 47225568 47226585 1017 0
H3ac HepG2E 47225344 47226689 1345 0
RARA MCF7GSE15244 47221512 47221940 428 0
RARG MCF7GSE15244 47221405 47221940 535 0
RARG MCF7GSE15244 47225823 47226546 723 0
TAF HelaGSE8489 47221691 47221940 249 0
TAF HelaGSE8489 47225881 47226651 770 0
TFAP2C MCF7GSE21234 47221476 47222140 664 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1025 Unknown pSILAC miR-16 ACP2 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000134575 n_a n_a n_a "epithelium, lymphoblast, lymphocyte, leukocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018