AutismKB 2.0

Annotation Detail for PLA2G4A


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Basic Information Top
Gene Symbol:PLA2G4A ( MGC126350,PLA2G4,cPLA2-alpha )
Gene Full Name: phospholipase A2, group IVA (cytosolic, calcium-dependent)
Band: 1q31.1
Quick LinksEntrez ID:5321; OMIM: 600522; Uniprot ID:PA24A_HUMAN; ENSEMBL ID: ENSG00000116711; HGNC ID: 9035
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
268Phosphothreonine.
434Phosphoserine.
435Phosphoserine.
437Phosphoserine.
505Phosphoserine; by MAPK.
535Phosphotyrosine.
727Phosphoserine.
729Phosphoserine.
Location(AA) Modifications Resource
228PhosphoserinePhospho.ELM 6.0
431PhosphoserinePhospho.ELM 6.0
437PhosphoserinePhospho.ELM 6.0
437Phosphoserine.Swiss-Prot 53.0
454PhosphoserinePhospho.ELM 6.0
505Phosphoserine (MAPK1;MAPK
505Phosphoserine (by MAPK).Swiss-Prot 53.0
515Phosphoserine (CaM-KIIalpha)Phospho.ELM 6.0
727Phosphoserine.Swiss-Prot 53.0
727PhosphoserinePhospho.ELM 6.0
729Phosphoserine.Swiss-Prot 53.0
729PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
60Phosphothreonine(PKA)HMM predict
72N-linkedHMM predict
238SulfotyrosineHMM predict
258N-linkedHMM predict
262N-linkedHMM predict
309N-linkedHMM predict
313Phosphoserine(CDC2)HMM predict
410Phosphoserine(ATM)HMM predict
416Phosphothreonine(CK2)HMM predict
423N-linkedHMM predict
432N-linkedHMM predict
435Phosphoserine(ATM)HMM predict
435Phosphoserine(CK2)HMM predict
435Phosphoserine(CK1)HMM predict
437Phosphoserine(CK1)HMM predict
437Phosphoserine(ATM)HMM predict
454Phosphoserine(CK1)HMM predict
499N-linkedHMM predict
505Phosphoserine(ATM)HMM predict
505Phosphoserine(CDC2)HMM predict
505Phosphoserine(MAPK)HMM predict
515Phosphoserine(CK2)HMM predict
584Phosphoserine(CDK)HMM predict
659Phosphothreonine(PKC)HMM predict
659Phosphothreonine(CK2)HMM predict
722N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024420
  • Location:chr1 185064654-185224727
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 185063227 185063533 306 1275
CBP T30-glioblastomaGSE21026 185063251 185063445 194 1307
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
STAT1 HeLaGSE12782 185241769 185243428 1659 17871
STAT1 HeLaGSE12783 185241769 185243394 1625 17854
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 185221748 185221992 244 0
CTCF CD4SISSRdata 185221748 185221992 244 0
CTCF G2GSE9613 185221731 185222029 298 0
H3K4me3 colorectalcancer 185064673 185065116 443 0
Nanog ESGSE20650 185203638 185204073 435 0
Nanog hESGSE18292 185221745 185222090 345 0
P300 T30-glioblastomaGSE21026 185210386 185211265 879 0
PolII HeLaGSE12783 185064472 185065949 1477 0
PolII HeLaGSE12783 185069546 185071091 1545 0
hScc1 BcellGSE12603 185220745 185221011 266 0
hScc1 BcellGSE12603 185221581 185222124 543 0
hScc1 CdLSGSE12603 185064565 185065305 740 0
hScc1 CdLSGSE12603 185084854 185085434 580 0
hScc1 CdLSGSE12603 185221515 185222163 648 0
hScc1 G2GSE9613 185221617 185222085 468 0
p63 keratinocytesGSE17611 185094575 185095408 833 0
p63 keratinocytesGSE17611 185111373 185112244 871 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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