AutismKB 2.0

Annotation Detail for PLAT


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Basic Information Top
Gene Symbol:PLAT ( DKFZp686I03148,T-PA,TPA )
Gene Full Name: plasminogen activator, tissue
Band: 8p11.21
Quick LinksEntrez ID:5327; OMIM: 173370; Uniprot ID:TPA_HUMAN; ENSEMBL ID: ENSG00000104368; HGNC ID: 9051
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
96O-linked (Fuc).
152N-linked (GlcNAc...).
219N-linked (GlcNAc...); partial.
483N-linked (GlcNAc...).
Location(AA) Modifications Resource
96O-linked (Fuc)./FTId=CAR
152N-linked (GlcNAc...).Swiss-Prot 53.0
219N-linked (GlcNAc...); partial./FTId=CAR
483N-linked (GlcNAc...)./FTId=CAR
Location(AA) Modification Resource
23Phosphoserine(ATM)HMM predict
140Phosphoserine(IKK)HMM predict
205O-linkedHMM predict
219N-linkedHMM predict
228Phosphoserine(IKK)HMM predict
232Phosphoserine(IKK)HMM predict
253N-linkedHMM predict
295O-linkedHMM predict
305Phosphoserine(ATM)HMM predict
305Phosphoserine(CAMK2)HMM predict
392Phosphotyrosine(Jak)HMM predict
403Phosphotyrosine(INSR)HMM predict
403Phosphotyrosine(Syk)HMM predict
449Phosphotyrosine(EGFR)HMM predict
449Phosphotyrosine(INSR)HMM predict
478Phosphoserine(IKK)HMM predict
483N-linkedHMM predict
489N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000930
  • Location:chr8 42151911-42184350
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42184223 42184653 430 88
CTCF G2GSE9613 42194753 42195070 317 10561
CTCF G2GSE9613 42197927 42198317 390 13772
Fos K562GSE19551 42186324 42186847 523 2235
H3K27me3 colorectalcancer 42185212 42185610 398 1061
H3K27me3 colorectalcancer 42186218 42186685 467 2101
Myc K562GSE19551 42191388 42192418 1030 7553
Rb GrowingGSE19898 42184221 42184485 264 3
TFAP2C MCF7GSE21234 42186317 42186810 493 2213
p130 QuiescentGSE19898 42184265 42184457 192 11
p130 SenescentGSE19898 42184150 42184584 434 17
p130 shRbSenescentGSE19898 42184116 42184636 520 26
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 42150519 42150549 30 1378
Oct1 HelaGSE14283 42150518 42150548 30 1379
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42164151 42164444 293 0
CTCF G2GSE9613 42167489 42168180 691 0
CTCF G2GSE9613 42169634 42170023 389 0
ER MCF7GSE19013 42178155 42178932 777 0
ER MCF7GSE19013 42183346 42184096 750 0
FOXA1 MCF7GSE15244 42176549 42176767 218 0
Fos K562GSE19551 42172769 42173362 593 0
H3K27me3 colorectalcancer 42172365 42174347 1982 0
H3K27me3 colorectalcancer 42182650 42184688 2038 0
P300 T30-glioblastomaGSE21026 42172617 42173681 1064 0
Rb GrowingGSE19898 42182952 42183199 247 0
Rb QuiescentGSE19898 42184160 42184421 261 0
Rb SenescentGSE19898 42184187 42184430 243 0
Rb shRbSenescenceGSE19898 42184198 42184400 202 0
VDR GM10855-stimGSE22484 42158181 42160399 2218 0
hScc1 BcellGSE12603 42164007 42164563 556 0
hScc1 CdLSGSE12603 42154131 42154894 763 0
hScc1 CdLSGSE12603 42165606 42165870 264 0
p130 QuiescentGSE19898 42184065 42184260 195 0
p130 SenescentGSE19898 42173018 42173578 560 0
p130 SenescentGSE19898 42183115 42183403 288 0
p130 shRbQuiescentGSE19898 42173190 42173559 369 0
p130 shRbSenescentGSE19898 42173133 42173409 276 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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