AutismKB 2.0

Annotation Detail for PLCB2


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Basic Information Top
Gene Symbol:PLCB2 ( FLJ38135 )
Gene Full Name: phospholipase C, beta 2
Band: 15q15.1
Quick LinksEntrez ID:5330; OMIM: 604114; Uniprot ID:PLCB2_HUMAN; ENSEMBL ID: ENSG00000137841; HGNC ID: 9055
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
18Phosphoserine(ATM)HMM predict
141N-linkedHMM predict
208PhosphotyrosineHMM predict
237Phosphothreonine(PKC)HMM predict
324N-linkedHMM predict
328N-linkedHMM predict
330Phosphotyrosine(Syk)HMM predict
345Phosphotyrosine(Abl)HMM predict
399Phosphoserine(CDC2)HMM predict
468O-linkedHMM predict
477Phosphothreonine(CK2)HMM predict
484O-linkedHMM predict
485O-linkedHMM predict
485Phosphoserine(ATM)HMM predict
514Phosphoserine(CK2)HMM predict
539Phosphotyrosine(SRC)HMM predict
539Phosphotyrosine(INSR)HMM predict
539Phosphotyrosine(Syk)HMM predict
578Phosphotyrosine(INSR)HMM predict
611Phosphotyrosine(Syk)HMM predict
611Phosphotyrosine(INSR)HMM predict
719Phosphoserine(CDC2)HMM predict
800Phosphotyrosine(INSR)HMM predict
845Phosphoserine(MAPK)HMM predict
845Phosphoserine(CDC2)HMM predict
845Phosphoserine(CDK)HMM predict
859O-linkedHMM predict
859Phosphoserine(IKK)HMM predict
859O-linkedHMM predict
860N-linkedHMM predict
862Phosphoserine(CDC2)HMM predict
884Phosphoserine(IKK)HMM predict
995Phosphotyrosine(EGFR)HMM predict
995Phosphotyrosine(SRC)HMM predict
995Phosphotyrosine(Syk)HMM predict
1034N-linkedHMM predict
1072N-linkedHMM predict
1073N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004573
  • Location:chr15 38367391-38387465
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 38389248 38389638 390 1978
H3ac HepG2E 38392625 38392836 211 5265
Myc hESGSE17917 38389611 38389834 223 2257
Oct1 HelaGSE14283 38394174 38394271 97 6757
Pol2 GM12878GSE19551 38387033 38387981 948 42
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 38365471 38365929 458 1692
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 38367392 38367673 281 0
CTCF G2GSE9613 38370535 38371132 597 0
CTCF G2GSE9613 38378047 38378426 379 0
CTCF G2GSE9613 38381651 38382004 353 0
CTCF G2GSE9613 38382577 38382861 284 0
CTCF G2GSE9613 38386235 38387671 1436 0
Oct1 HelaGSE14283 38377910 38377953 43 0
hScc1 BcellGSE12603 38370353 38371193 840 0
hScc1 BcellGSE12603 38381651 38382101 450 0
hScc1 BcellGSE12603 38382499 38382791 292 0
hScc1 BcellGSE12603 38385555 38386013 458 0
hScc1 BcellGSE12603 38387072 38387642 570 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018