Annotation Detail for PLCG1
Basic Information Top
| Gene Symbol: | PLCG1 ( NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1 ) |
|---|---|
| Gene Full Name: | phospholipase C, gamma 1 |
| Band: | 20q12 |
| Quick Links | Entrez ID:5335; OMIM: 172420; Uniprot ID:PLCG1_HUMAN; ENSEMBL ID: ENSG00000124181; HGNC ID: 9065 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 2 | N-acetylalanine. | |
| 6 | Phosphoserine. | |
| 379 | Phosphotyrosine (By similarity). | |
| 481 | Phosphotyrosine (By similarity). | |
| 506 | Phosphotyrosine (By similarity). | |
| 525 | Phosphoserine. | |
| 771 | Phosphotyrosine. | |
| 775 | Phosphotyrosine. | |
| 783 | Phosphotyrosine. | |
| 977 | Phosphotyrosine. | |
| 1221 | Phosphoserine. | |
| 1248 | Phosphoserine (By similarity). | |
| 1253 | Phosphotyrosine. | |
| 1263 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 472 | Phosphotyrosine (EGFR;FGFR1) | Phospho.ELM 6.0 |
| 771 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 771 | Phosphotyrosine (Syk;TRKB;Sky) | Phospho.ELM 6.0 |
| 775 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 775 | Phosphotyrosine | Phospho.ELM 6.0 |
| 783 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 783 | Phosphotyrosine (Syk;TRKB;EGF) | Phospho.ELM 6.0 |
| 1248 | Phosphoserine (PKC alpha;PK) | Phospho.ELM 6.0 |
| 1253 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 1253 | Phosphotyrosine (TRKB;EGFR;FG) | Phospho.ELM 6.0 |
| 1253 | Phosphotyrosine (PDGFR beta;E) | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 6 | Phosphoserine(IKK) | HMM predict |
| 93 | Sulfotyrosine | HMM predict |
| 93 | Phosphotyrosine(Syk) | HMM predict |
| 93 | Phosphotyrosine | HMM predict |
| 125 | Phosphothreonine(CK2) | HMM predict |
| 250 | Phosphoserine(PKG) | HMM predict |
| 349 | Phosphoserine(CK1) | HMM predict |
| 472 | Phosphotyrosine(Abl) | HMM predict |
| 472 | Phosphotyrosine(SRC) | HMM predict |
| 472 | Phosphotyrosine(Syk) | HMM predict |
| 472 | Phosphotyrosine(EGFR) | HMM predict |
| 518 | Phosphotyrosine(INSR) | HMM predict |
| 518 | Phosphotyrosine(Syk) | HMM predict |
| 524 | Phosphoserine(CK1) | HMM predict |
| 525 | Phosphoserine(CK1) | HMM predict |
| 539 | Phosphoserine(CK2) | HMM predict |
| 540 | Phosphoserine(CK1) | HMM predict |
| 541 | Phosphoserine(CK1) | HMM predict |
| 654 | Phosphoserine(PKG) | HMM predict |
| 771 | Phosphotyrosine(EGFR) | HMM predict |
| 771 | Phosphotyrosine(SRC) | HMM predict |
| 771 | Sulfotyrosine | HMM predict |
| 783 | Phosphotyrosine(EGFR) | HMM predict |
| 932 | O-linked | HMM predict |
| 938 | Phosphothreonine(PKC) | HMM predict |
| 972 | Phosphothreonine(PKC) | HMM predict |
| 1023 | Phosphotyrosine(Syk) | HMM predict |
| 1023 | Phosphotyrosine(INSR) | HMM predict |
| 1042 | Phosphothreonine(CDC2) | HMM predict |
| 1253 | Phosphotyrosine(EGFR) | HMM predict |
- RefSeq ID: NM_002660
- Location:chr20 39199574-39237770
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 39197296 | 39197538 | 242 | 2158 |
| CTCF | CD4 | SISSRdata | 39197296 | 39197538 | 242 | 2158 |
| CTCF | G2 | GSE9613 | 39196490 | 39197843 | 1353 | 2408 |
| CTCF | G2 | GSE9613 | 39199398 | 39199712 | 314 | 20 |
| H3ac | HepG2 | E | 39196703 | 39198559 | 1856 | 1944 |
| PHF8 | HeLa | GSE20725 | 39198555 | 39200455 | 1900 | 70 |
| hScc1 | Bcell | GSE12603 | 39197129 | 39197737 | 608 | 2142 |
| hScc1 | Bcell | GSE12603 | 39198876 | 39199784 | 908 | 245 |
| hScc1 | CdLS | GSE12603 | 39197129 | 39197772 | 643 | 2124 |
| p130 | shRbSenescent | GSE19898 | 39198417 | 39199190 | 773 | 771 |
| p63 | keratinocytes | GSE17611 | 39195510 | 39196625 | 1115 | 3507 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 39235273 | 39235530 | 257 | 0 |
| CTCF | CD4 | SISSRdata | 39235273 | 39235530 | 257 | 0 |
| CTCF | G2 | GSE9613 | 39235253 | 39236003 | 750 | 0 |
| Fos | K562 | GSE19551 | 39211618 | 39212236 | 618 | 0 |
| H3ac | HepG2 | E | 39200137 | 39204471 | 4334 | 0 |
| H3ac | HepG2 | E | 39204965 | 39206144 | 1179 | 0 |
| H3ac | HepG2 | E | 39208127 | 39208930 | 803 | 0 |
| Rb | Growing | GSE19898 | 39200860 | 39200974 | 114 | 0 |
| Rb | Quiescent | GSE19898 | 39235231 | 39235504 | 273 | 0 |
| Rb | shRbSenescence | GSE19898 | 39200844 | 39200990 | 146 | 0 |
| USF1 | HepG2 | E | 39200248 | 39201250 | 1002 | 0 |
| USF1 | HepG2 | E | 39201502 | 39202146 | 644 | 0 |
| hScc1 | Bcell | GSE12603 | 39219016 | 39219590 | 574 | 0 |
| hScc1 | Bcell | GSE12603 | 39231158 | 39231430 | 272 | 0 |
| hScc1 | Bcell | GSE12603 | 39235014 | 39235870 | 856 | 0 |
| hScc1 | CdLS | GSE12603 | 39234806 | 39235845 | 1039 | 0 |
| hScc1 | G2 | GSE9613 | 39235014 | 39235928 | 914 | 0 |
| p63 | keratinocytes | GSE17611 | 39231481 | 39232537 | 1056 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-141 | hsa-mir-141 | 12 | 20514023 |
| hsa-miR-141* | hsa-mir-141 | 12 | 20514023 |
| hsa-miR-200a | hsa-mir-200a | 1 | 20514023 |
| hsa-miR-200a* | hsa-mir-200a | 1 | 20514023 |
| hsa-miR-200b | hsa-mir-200b | 1 | 20514023 |
| hsa-miR-200b* | hsa-mir-200b | 1 | 20514023 |
| hsa-miR-200c | hsa-mir-200c | 12 | 20514023 |
| hsa-miR-200c* | hsa-mir-200c | 12 | 20514023 |
| hsa-miR-429 | hsa-mir-429 | 1 | 20514023 |
| No data |
| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16373 | mRNA | PLCG1 | chr20 | 39199574 | 39237771 | 145 | mRNA | chr20 | 39160382 | 39200054 | Sense/Antisense (SA) pairs | |