AutismKB 2.0

Annotation Detail for SERPINF2


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Basic Information Top
Gene Symbol:SERPINF2 ( A2AP,AAP,ALPHA-2-PI,API,PLI )
Gene Full Name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Band: 17p13.3
Quick LinksEntrez ID:5345; OMIM: 613168; Uniprot ID:A2AP_HUMAN; ENSEMBL ID: ENSG00000167711; HGNC ID: 9075
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
126N-linked (GlcNAc...).
295N-linked (GlcNAc...).
309N-linked (GlcNAc...).
316N-linked (GlcNAc...) (Potential).
484Sulfotyrosine.
Location(AA) Modifications Resource
41Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-322 in alpha-fibrinogen).Swiss-Prot 53.0
126N-linked (GlcNAc...).Swiss-Prot 53.0
295N-linked (GlcNAc...).Swiss-Prot 53.0
309N-linked (GlcNAc...).Swiss-Prot 53.0
316N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
484Sulfotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
20Phosphoserine(ATM)HMM predict
75Phosphothreonine(CDK)HMM predict
75Phosphothreonine(MAPK)HMM predict
109Phosphoserine(CDC2)HMM predict
109Phosphoserine(MAPK)HMM predict
126N-linkedHMM predict
140O-linkedHMM predict
250Phosphothreonine(PKC)HMM predict
405PhosphoserineHMM predict
437N-linkedHMM predict
474LeucineHMM predict
484SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000934
  • Location:chr17 1592879-1605307
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 1605219 1605600 381 102
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1598658 1598943 285 0
CTCF G2GSE9613 1600673 1601185 512 0
H3ac HepG2E 1594721 1595015 294 0
TFAP2C MCF7GSE21234 1602347 1602913 566 0
hScc1 BcellGSE12603 1595691 1595986 295 0
hScc1 BcellGSE12603 1596918 1597092 174 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
10461 mRNA SERPINF2 chr17 1595035 1605309 205 mRNA chr17 1600512 1603539Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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