Annotation Detail for ATP6V0A1

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Basic Information Top

Gene Symbol:	ATP6V0A1 ( ATP6N1,ATP6N1A,DKFZp781J1951,Stv1,VPP1,Vph1,a1 )
Gene Full Name:	ATPase, H+ transporting, lysosomal V0 subunit a1
Band:	17q21.2
Quick Links	Entrez ID:535; OMIM: 192130; Uniprot ID:VPP1_HUMAN; ENSEMBL ID: ENSG00000033627; HGNC ID: 865
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
250	Phosphothreonine (By similarity).
364	Phosphotyrosine (By similarity).

Location(AA)	Modifications	Resource
250	Phosphothreonine (By similarity).	Swiss-Prot 53.0
273	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
365	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
488	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	37858626	37858769	143	5690
TAF	k562	GSE8489	37862497	37863506	1009	1386

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	37932736	37933166	430	4830
CTCF	CD4	SISSRdata	37932736	37933166	430	4830
CTCF	Hela	GSE12889	37932855	37933163	308	4888
CTCF	Jurkat	GSE12889	37932865	37933053	188	4838
CTCF	G2	GSE9613	37932929	37933182	253	4934
Oct4	hES	GSE17917	37932843	37933065	222	4833
TAFII	hES	GSE17917	37932656	37933315	659	4864
hScc1	Bcell	GSE12603	37932811	37933182	371	4875
hScc1	CdLS	GSE12603	37932700	37933182	482	4820

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	37923008	37923360	352
CTCF	CD4	SISSRdata	37923008	37923360	352
CTCF	G2	GSE9613	37922902	37923512	610
H3K4me3	colorectal	cancer	37864554	37865090	536
H3ac	HepG2	E	37864554	37866997	2443
NRSF	Jurkat	GSE13047	37864706	37866049	1343
NRSF	mAb	Jurkat	37864307	37866997	2690
NRSF-mono	Jurkat	QuESTdata	37864097	37865958	1861
NRSF-poly	Jurkat	QuESTdata	37864147	37866384	2237
Oct1	H2O2-Hela	GSE14283	37907083	37907113	30
Oct1	Hela	GSE14283	37907081	37907110	29
PHF8	293T	GSE20725	37863868	37865065	1197
PolII	HeLa	GSE12783	37863897	37865203	1306
USF1	HepG2	E	37924613	37926516	1903
hScc1	Bcell	GSE12603	37922902	37923439	537
hScc1	CdLS	GSE12603	37922862	37923548	686
p130	shRbQuiescent	GSE19898	37925882	37926388	506

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	21097505
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	21097505
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040
hsa-miR-375	hsa-mir-375	2	20584986

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
834	Unknown	pSILAC	let-7b	ATP6V0A1	down <25%	18668040
1137	Unknown	pSILAC	miR-1	ATP6V0A1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000033627		n_a	n_a	n_a	"lymphocyte, leukocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000033627		n_a	n_a	n_a	"lymphocyte, leukocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018