AutismKB 2.0

Annotation Detail for PLOD2


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Basic Information Top
Gene Symbol:PLOD2 ( LH2,TLH )
Gene Full Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Band: 3q24
Quick LinksEntrez ID:5352; OMIM: 601865; Uniprot ID:PLOD2_HUMAN; ENSEMBL ID: ENSG00000152952; HGNC ID: 9082
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
63N-linked (GlcNAc...) (Potential).
209N-linked (GlcNAc...).
297N-linked (GlcNAc...) (Potential).
320Phosphothreonine.
323Phosphotyrosine.
365N-linked (GlcNAc...) (Potential).
522N-linked (GlcNAc...).
696N-linked (GlcNAc...) (Potential).
725N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
63N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
209N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
297N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
365N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
522N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
696N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
725N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
33Phosphoserine(IKK)HMM predict
63N-linkedHMM predict
209N-linkedHMM predict
245Phosphotyrosine(EGFR)HMM predict
268Phosphotyrosine(INSR)HMM predict
356Phosphothreonine(PKC)HMM predict
367Phosphoserine(CK2)HMM predict
367Phosphoserine(ATM)HMM predict
387SulfotyrosineHMM predict
437Phosphotyrosine(Syk)HMM predict
444Phosphotyrosine(EGFR)HMM predict
444Phosphotyrosine(INSR)HMM predict
517Phosphoserine(PKG)HMM predict
522N-linkedHMM predict
527N-linkedHMM predict
528N-linkedHMM predict
662Phosphoserine(PKB)HMM predict
725N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000935
  • Location:chr3 147269917-147361971
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 147365434 147366114 680 3803
H3K4me3 colorectalcancer 147362048 147362362 314 234
HIF1 HypoHepG2 147361617 147362440 823 57
RARA MCF7GSE15244 147364336 147364822 486 2608
RARA MCF7GSE15244 147365434 147366048 614 3770
RARA MCF7GSE15244 147366860 147367207 347 5062
RARG MCF7GSE15244 147362048 147362480 432 293
RARG MCF7GSE15244 147365434 147365978 544 3735
RARG MCF7GSE15244 147366919 147367207 288 5092
STAT1 HeLaGSE12783 147366687 147368796 2109 5770
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 147360666 147361976 1310 0
ER MCF7GSE19013 147294537 147295217 680 0
ER MCF7GSE19013 147315701 147316745 1044 0
ER MCF7GSE19013 147340389 147341072 683 0
FOXA1 MCF7GSE15244 147315976 147316667 691 0
FOXA1 MCF7GSE15244 147360604 147361153 549 0
H3K4me3 colorectalcancer 147360277 147361195 918 0
H3ac HepG2E 147358361 147359691 1330 0
H3ac HepG2E 147360164 147361195 1031 0
Oct1 H2O2-HelaGSE14283 147336446 147336476 30 0
Oct1 HelaGSE14283 147274757 147274794 37 0
Oct1 HelaGSE14283 147336446 147336526 80 0
Oct4 ESGSE20650 147335064 147335366 302 0
Oct4 hESGSE17917 147334944 147335383 439 0
RARA MCF7GSE15244 147315934 147316667 733 0
RARA MCF7GSE15244 147360164 147361125 961 0
RARG MCF7GSE15244 147315740 147316667 927 0
RARG MCF7GSE15244 147360604 147361125 521 0
TFAP2C MCF7GSE21234 147361362 147362257 895 0
hScc1 BcellGSE12603 147361089 147361834 745 0
hScc1 G2GSE9613 147361125 147361976 851 0
p130 shRbSenescentGSE19898 147360954 147361143 189 0
p130 shRbSenescentGSE19898 147361214 147361481 267 0
p130 shRbSenescentGSE19898 147361829 147362114 285 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
18805 EST chr3 147264603 147305687 35760 mRNA PLOD2 chr3 147269927 147361640 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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