AutismKB 2.0

Annotation Detail for PLP1


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Basic Information Top
Gene Symbol:PLP1 ( HLD1,MMPL,PLP,PLP/DM20,PMD,SPG2 )
Gene Full Name: proteolipid protein 1
Band: Xq22.2
Quick LinksEntrez ID:5354; OMIM: 300401; Uniprot ID:MYPR_HUMAN; ENSEMBL ID: ENSG00000123560; HGNC ID: 9086
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
7S-palmitoylHMM predict
10S-palmitoylHMM predict
58SulfotyrosineHMM predict
124MethylarginineHMM predict
134Phosphoserine(CK1)HMM predict
139S-palmitoylHMM predict
141S-palmitoylHMM predict
160Phosphothreonine(PKC)HMM predict
193O-linkedHMM predict
194O-linkedHMM predict
222Phosphoserine(IKK)HMM predict
250Phosphothreonine(PKC)HMM predict
271MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000533
  • Location:chrX 102918409-102934200
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102908943 102909167 224 9355
CTCF G2GSE9613 102915115 102916288 1173 2708
Oct1 HelaGSE14283 102900174 102900212 38 18217
Oct1 HelaGSE14283 102916181 102916226 45 2206
hScc1 G2GSE9613 102908907 102909167 260 9373
hScc1 G2GSE9613 102914989 102916575 1586 2628
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102949293 102949558 265 15225
Fos K562GSE19551 102939008 102939430 422 5019
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102932828 102932981 153 0
Oct4 hESGSE17917 102922520 102922871 351 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
27977 mRNA PLP1 chrX 102837898 102853690 147 mRNA RAB9B chrX 102837648 102893332Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018