AutismKB 2.0

Annotation Detail for PLP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PLP2 ( A4,A4LSB,MGC126187 )
Gene Full Name: proteolipid protein 2 (colonic epithelium-enriched)
Band: Xp11.23
Quick LinksEntrez ID:5355; OMIM: 300112; Uniprot ID:PLP2_HUMAN; ENSEMBL ID: ENSG00000102007; HGNC ID: 9087
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
18N-linked (GlcNAc...) (Potential).
108N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
18N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
108N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
18N-linkedHMM predict
49Phosphotyrosine(INSR)HMM predict
130Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002668
  • Location:chrX 48915216-48918378
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 48915099 48915888 789 0
CTCF G2GSE9613 48916638 48916949 311 0
Oct1 H2O2-HelaGSE14283 48916881 48916911 30 0
PHF8 HeLaGSE20725 48914860 48916012 1152 0
hScc1 G2GSE9613 48915138 48915980 842 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
392 Unknown MicroArray miR-124 PLP2 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000102007 G1-to-S transition n_a n_a n_a n_a
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
27632 mRNA PLP2 chrX 48784643 48787808 287 EST chrX 48787521 48788018Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved