AutismKB 2.0

Annotation Detail for PLSCR1


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Basic Information Top
Gene Symbol:PLSCR1 ( MMTRA1B )
Gene Full Name: phospholipid scramblase 1
Band: 3q24
Quick LinksEntrez ID:5359; OMIM: 604170; Uniprot ID:PLS1_HUMAN; ENSEMBL ID: ENSG00000188313; HGNC ID: 9092
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
25WW-binding 1 (Potential).
26SH3-binding 1 (Potential).
36WW-binding 2 (Potential).
50SH3-binding 2 (Potential).
69Phosphotyrosine; by ABL.
74Phosphotyrosine; by ABL.
92SH3-binding 3 (Potential).
161Phosphothreonine; by PKC.
Location(AA) Modifications Resource
69Phosphotyrosine (by ABL).Swiss-Prot 53.0
69Phosphotyrosine (Abl;Src)Phospho.ELM 6.0
74Phosphotyrosine (by ABL).Swiss-Prot 53.0
74Phosphotyrosine (Abl;Src)Phospho.ELM 6.0
161Phosphothreonine (by PKC).Swiss-Prot 53.0
234S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
237S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
239S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
240S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
9N-linkedHMM predict
28O-linkedHMM predict
28O-linkedHMM predict
37O-linkedHMM predict
37O-linkedHMM predict
45O-linkedHMM predict
54O-linkedHMM predict
54Phosphoserine(IKK)HMM predict
69Phosphotyrosine(Abl)HMM predict
74Phosphotyrosine(Abl)HMM predict
161Phosphothreonine(PKC)HMM predict
188S-palmitoylHMM predict
189S-palmitoylHMM predict
272Phosphothreonine(CK2)HMM predict
310Phosphoserine(CK1)HMM predict
310Phosphoserine(ATM)HMM predict
310Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021105
  • Location:chr3 147715657-147745185
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 147751625 147752062 437 6658
Jun K562GSE19551 147751591 147751895 304 6558
Myc K562GSE19551 147754908 147755299 391 9918
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T30-glioblastomaGSE21026 147706713 147707782 1069 8410
RARA MCF7GSE15244 147707437 147708052 615 7913
TAF HelaGSE8489 147707437 147707833 396 8023
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 147744954 147745083 129 0
ER MCF7GSE19013 147744709 147745175 466 0
FOXA1 MCF7GSE15244 147744910 147745361 451 0
H3K4me3 colorectalcancer 147744004 147744571 567 0
H3ac HepG2E 147743638 147745399 1761 0
PHF8 HeLaGSE20725 147744552 147745533 981 0
RARA MCF7GSE15244 147725457 147725919 462 0
Rb GrowingGSE19898 147745064 147745305 241 0
STAT1 HeLaGSE12782 147741975 147745971 3996 0
STAT1 HeLaGSE12783 147742009 147745794 3785 0
p130 SenescentGSE19898 147744767 147745354 587 0
p130 shRbSenescentGSE19898 147744775 147745453 678 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018