AutismKB 2.0

Annotation Detail for PLXNA1


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Basic Information Top
Gene Symbol:PLXNA1 ( DKFZp761P19121,NOV,NOVP,PLEXIN-A1,PLXN1 )
Gene Full Name: plexin A1
Band: 3q21.3
Quick LinksEntrez ID:5361; OMIM: 601055; Uniprot ID:PLXA1_HUMAN; ENSEMBL ID: ENSG00000114554; HGNC ID: 9099
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
77N-linked (GlcNAc...).
122Phosphotyrosine (By similarity).
660N-linked (GlcNAc...) (Potential).
672N-linked (GlcNAc...) (Potential).
701N-linked (GlcNAc...) (Potential).
1043N-linked (GlcNAc...).
1187N-linked (GlcNAc...) (Potential).
1212N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
77N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
660N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
672N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
701N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1043N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1187N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1212N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
37Phosphoserine(ATM)HMM predict
245SulfotyrosineHMM predict
245Phosphotyrosine(Syk)HMM predict
493Phosphoserine(CDK)HMM predict
498Phosphotyrosine(Jak)HMM predict
576O-linkedHMM predict
578Phosphoserine(IKK)HMM predict
597N-linkedHMM predict
608Phosphoserine(CK2)HMM predict
660N-linkedHMM predict
666Phosphoserine(IKK)HMM predict
672N-linkedHMM predict
716Phosphotyrosine(SRC)HMM predict
742Phosphotyrosine(EGFR)HMM predict
751Phosphoserine(CDC2)HMM predict
761N-linkedHMM predict
769N-linkedHMM predict
914Phosphotyrosine(EGFR)HMM predict
914Phosphotyrosine(INSR)HMM predict
957Phosphothreonine(PKA)HMM predict
967Phosphoserine(CDK)HMM predict
967Phosphoserine(CDC2)HMM predict
1043N-linkedHMM predict
1075Phosphothreonine(PKC)HMM predict
1098N-linkedHMM predict
1140N-linkedHMM predict
1147SulfotyrosineHMM predict
1156Phosphoserine(CDC2)HMM predict
1156Phosphoserine(MAPK)HMM predict
1156Phosphoserine(CDK)HMM predict
1167Phosphoserine(CDC2)HMM predict
1187N-linkedHMM predict
1188Phosphotyrosine(INSR)HMM predict
1194O-linkedHMM predict
1200O-linkedHMM predict
1212N-linkedHMM predict
1220Phosphothreonine(PKC)HMM predict
1277Phosphothreonine(PKC)HMM predict
1382Phosphoserine(PKB)HMM predict
1435Phosphoserine(PKG)HMM predict
1435Phosphoserine(PKB)HMM predict
1487Phosphoserine(CK1)HMM predict
1487Phosphoserine(PKG)HMM predict
1545Phosphotyrosine(Abl)HMM predict
1546Phosphoserine(ATM)HMM predict
1586Phosphothreonine(PKC)HMM predict
1609N-linkedHMM predict
1612N-linkedHMM predict
1623Phosphotyrosine(INSR)HMM predict
1629PhosphothreonineHMM predict
1631Phosphoserine(IKK)HMM predict
1631Phosphoserine(PKB)HMM predict
1632Phosphoserine(CDK)HMM predict
1632Phosphoserine(CDC2)HMM predict
1795Phosphoserine(CDC2)HMM predict
1827Phosphoserine(ATM)HMM predict
1844Phosphoserine(ATM)HMM predict
1848Phosphoserine(IKK)HMM predict
1858SulfotyrosineHMM predict
1883Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018