AutismKB 2.0

Annotation Detail for PLXNB1


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Basic Information Top
Gene Symbol:PLXNB1 ( KIAA0407,MGC149167,PLEXIN-B1,PLXN5,SEP )
Gene Full Name: plexin B1
Band: 3p21.31
Quick LinksEntrez ID:5364; OMIM: 601053; Uniprot ID:PLXB1_HUMAN; ENSEMBL ID: ENSG00000164050; HGNC ID: 9103
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
31N-linked (GlcNAc...) (Potential).
334N-linked (GlcNAc...) (Potential).
543N-linked (GlcNAc...) (Potential).
1183N-linked (GlcNAc...) (Potential).
1253N-linked (GlcNAc...).
1330N-linked (GlcNAc...).
Location(AA) Modifications Resource
31N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
334N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
543N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1183N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1253N-linked (GlcNAc...).Swiss-Prot 53.0
1330N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
31N-linkedHMM predict
104Phosphoserine(MAPK)HMM predict
142Phosphotyrosine(EGFR)HMM predict
259SulfotyrosineHMM predict
259Phosphotyrosine(Syk)HMM predict
273Phosphotyrosine(INSR)HMM predict
283Phosphothreonine(PKC)HMM predict
298O-linkedHMM predict
304Phosphothreonine(PKC)HMM predict
310O-linkedHMM predict
334N-linkedHMM predict
358SulfotyrosineHMM predict
382Phosphothreonine(CDC2)HMM predict
382Phosphothreonine(MAPK)HMM predict
384O-linkedHMM predict
424Phosphoserine(ATM)HMM predict
442Phosphotyrosine(Abl)HMM predict
467Phosphotyrosine(Abl)HMM predict
508S-palmitoylHMM predict
543N-linkedHMM predict
590O-linkedHMM predict
590Phosphoserine(CDC2)HMM predict
594O-linkedHMM predict
674O-linkedHMM predict
681Phosphoserine(CDC2)HMM predict
681O-linkedHMM predict
691Phosphoserine(CDK)HMM predict
691Phosphoserine(ATM)HMM predict
691Phosphoserine(CDC2)HMM predict
691O-linkedHMM predict
693O-linkedHMM predict
693Phosphoserine(ATM)HMM predict
703O-linkedHMM predict
703Phosphothreonine(MAPK)HMM predict
718O-linkedHMM predict
720O-linkedHMM predict
725O-linkedHMM predict
725Phosphoserine(ATM)HMM predict
731Phosphoserine(IKK)HMM predict
734Phosphoserine(CDC2)HMM predict
736C-linkedHMM predict
744Phosphoserine(IKK)HMM predict
746O-linkedHMM predict
747Phosphoserine(CDC2)HMM predict
747Phosphoserine(ATM)HMM predict
750Phosphoserine(IKK)HMM predict
750O-linkedHMM predict
760Phosphoserine(ATM)HMM predict
760O-linkedHMM predict
763Phosphoserine(CDC2)HMM predict
763O-linkedHMM predict
781Phosphoserine(CK2)HMM predict
790Phosphoserine(MAPK)HMM predict
790Phosphoserine(CDC2)HMM predict
793Phosphoserine(MAPK)HMM predict
793Phosphoserine(IKK)HMM predict
793Phosphoserine(CDC2)HMM predict
795O-linkedHMM predict
893SulfotyrosineHMM predict
895Phosphotyrosine(Syk)HMM predict
1023Phosphoserine(ATM)HMM predict
1089Phosphothreonine(PKA)HMM predict
1120Phosphotyrosine(Syk)HMM predict
1150MethylarginineHMM predict
1183N-linkedHMM predict
1220Phosphoserine(CDC2)HMM predict
1224O-linkedHMM predict
1224O-linkedHMM predict
1253N-linkedHMM predict
1282Phosphothreonine(MAPK)HMM predict
1297Phosphoserine(ATM)HMM predict
1313O-linkedHMM predict
1317Phosphoserine(IKK)HMM predict
1330N-linkedHMM predict
1332Phosphoserine(ATM)HMM predict
1368N-linkedHMM predict
1412Phosphoserine(CK1)HMM predict
1515Phosphoserine(PKG)HMM predict
1598Phosphothreonine(PKC)HMM predict
1630Phosphoserine(PKB)HMM predict
1702Phosphoserine(PKG)HMM predict
1789Phosphotyrosine(Syk)HMM predict
1824Phosphoserine(CK1)HMM predict
1835Phosphothreonine(PKC)HMM predict
1864Phosphotyrosine(Jak)HMM predict
1864Phosphotyrosine(INSR)HMM predict
1864Phosphotyrosine(EGFR)HMM predict
1870Phosphothreonine(MAPK)HMM predict
1890Phosphoserine(CK2)HMM predict
1900MethylarginineHMM predict
1902Phosphoserine(PKC)HMM predict
1902Phosphoserine(PKG)HMM predict
1902Phosphoserine(PKA)HMM predict
1924Phosphoserine(CAMK2)HMM predict
2053Phosphotyrosine(EGFR)HMM predict
2059Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002673
  • Location:chr3 48420266-48441745
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 48441701 48442192 491 201
CTCF G2GSE9613 48444065 48444877 812 2726
H3ac HepG2E 48442031 48445102 3071 1821
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 48417297 48417623 326 2807
CTCF CD4SISSRdata 48417297 48417623 326 2807
CTCF G2GSE9613 48417408 48417696 288 2715
P300 T30-glioblastomaGSE21026 48418359 48419231 872 1472
hScc1 BcellGSE12603 48416452 48416627 175 3727
hScc1 BcellGSE12603 48417408 48417755 347 2685
hScc1 CdLSGSE12603 48417408 48417755 347 2685
hScc1 G2GSE9613 48417408 48417696 288 2715
p63 keratinocytesGSE17611 48418446 48419394 948 1347
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 48421708 48422162 454 0
CTCF G2GSE9613 48422799 48423774 975 0
CTCF G2GSE9613 48424736 48425865 1129 0
CTCF G2GSE9613 48426315 48426462 147 0
CTCF G2GSE9613 48426794 48427089 295 0
CTCF G2GSE9613 48427529 48427795 266 0
CTCF G2GSE9613 48428062 48428315 253 0
CTCF G2GSE9613 48430069 48432806 2737 0
CTCF G2GSE9613 48433598 48434438 840 0
CTCF G2GSE9613 48435220 48436852 1632 0
CTCF G2GSE9613 48437120 48437911 791 0
CTCF G2GSE9613 48439452 48441373 1921 0
hScc1 BcellGSE12603 48424736 48426537 1801 0
hScc1 BcellGSE12603 48431569 48431983 414 0
hScc1 BcellGSE12603 48440353 48440833 480 0
hScc1 G2GSE9613 48431569 48432806 1237 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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