Annotation Detail for PNOC

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Basic Information Top

Gene Symbol:	PNOC ( PPNOC )
Gene Full Name:	prepronociceptin
Band:	8p21.1
Quick Links	Entrez ID:5368; OMIM: 601459; Uniprot ID:PNOC_HUMAN; ENSEMBL ID: ENSG00000168081; HGNC ID: 9163
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:2 results

No data

Location(AA)	Modification	Resource
73	Phosphoserine(CDC2)	HMM predict
169	Phosphothreonine(PKA)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_006228
Location:chr8 28230567-28256784
strand:+

Upstream the gene:2 results
Downstream the gene:0 results
Inside the gene:16 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	28229536	28229658	122	971
RARG	MCF7	GSE15244	28229762	28229953	191	710

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	T30-glioblastoma	GSE21026	28254368	28255034	666	0
CTCF	CD4	GSE12889	28237755	28238035	280	0
CTCF	CD4	SISSRdata	28237755	28238035	280	0
CTCF	G2	GSE9613	28232050	28232307	257	0
CTCF	G2	GSE9613	28237581	28237989	408	0
CTCF	G2	GSE9613	28238546	28238776	230	0
FOXA1	DLD1	GSE12801	28254516	28254947	431	0
FOXA1	MCF7	GSE15244	28254417	28254840	423	0
GATA3	MCF7	GSE15244	28248240	28248910	670	0
Myc	K562	GSE19551	28237796	28238035	239	0
NRSF	Jurkat	SISSRdata	28242650	28242866	216	0
RNAII	Tamoxifen-MCF7	GSE14664	28236541	28236630	89	0
STAT1	HeLa	GSE12783	28232475	28234051	1576	0
hScc1	Bcell	GSE12603	28237509	28237989	480	0
hScc1	CdLS	GSE12603	28237443	28237989	546	0
hScc1	G2	GSE9613	28237474	28237956	482	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
25224	mRNA	PNOC	chr8	28230567	28256786	216	EST		chr8	28163498	28252691	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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