AutismKB 2.0

Annotation Detail for FXYD5


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Basic Information Top
Gene Symbol:FXYD5 ( DYSAD,IWU1,KCT1,OIT2,PRO6241,RIC )
Gene Full Name: FXYD domain containing ion transport regulator 5
Band: 19q13.12
Quick LinksEntrez ID:53827; OMIM: 606669; Uniprot ID:FXYD5_HUMAN; ENSEMBL ID: ENSG00000089327; HGNC ID: 4029
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
112Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
23Phosphothreonine(PKC)HMM predict
29Phosphoserine(CK1)HMM predict
29Phosphoserine(CK2)HMM predict
30O-linkedHMM predict
30Phosphoserine(CK2)HMM predict
58Phosphoserine(IKK)HMM predict
58Phosphoserine(CDK)HMM predict
58Phosphoserine(CDC2)HMM predict
58Phosphoserine(MAPK)HMM predict
62PhosphothreonineHMM predict
68Phosphothreonine(CDC2)HMM predict
68Phosphothreonine(MAPK)HMM predict
68Phosphothreonine(CDK)HMM predict
112O-linkedHMM predict
112Phosphoserine(CDC2)HMM predict
137Phosphotyrosine(EGFR)HMM predict
177S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014164
  • Location:chr19 40337466-40352624
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 40343955 40344595 640 0
Gata2 K562GSE18868 40348873 40350688 1815 0
H3K27me3 colorectalcancer 40338743 40339422 679 0
P300 T30-glioblastomaGSE21026 40345547 40346153 606 0
Rb GrowingGSE19898 40337708 40338012 304 0
Rb QuiescentGSE19898 40337709 40338053 344 0
Rb SenescentGSE19898 40337487 40338193 706 0
TFAP2C MCF7GSE21234 40345525 40346044 519 0
TFAP2C MCF7GSE21234 40350669 40351590 921 0
hScc1 BcellGSE12603 40337421 40337810 389 0
p130 SenescentGSE19898 40337585 40338127 542 0
p130 shRbQuiescentGSE19898 40337526 40338043 517 0
p130 shRbSenescentGSE19898 40337422 40337900 478 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018