AutismKB 2.0

Annotation Detail for DUOX1


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Basic Information Top
Gene Symbol:DUOX1 ( LNOX1,MGC138840,MGC138841,NOXEF1,THOX1 )
Gene Full Name: dual oxidase 1
Band: 15q21.1
Quick LinksEntrez ID:53905; OMIM: 606758; Uniprot ID:DUOX1_HUMAN; ENSEMBL ID: ENSG00000137857; HGNC ID: 3062
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
94N-linked (GlcNAc...) (Potential).
342N-linked (GlcNAc...) (Potential).
354N-linked (GlcNAc...) (Potential).
461N-linked (GlcNAc...) (Potential).
534N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
94N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
342N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
354N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
461N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
534N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
79Phosphoserine(IKK)HMM predict
94N-linkedHMM predict
158Phosphoserine(CDC2)HMM predict
158Phosphoserine(CDK)HMM predict
160PhosphoserineHMM predict
184Phosphoserine(IKK)HMM predict
307SulfotyrosineHMM predict
342N-linkedHMM predict
356Phosphoserine(PKA)HMM predict
461N-linkedHMM predict
534N-linkedHMM predict
701Phosphothreonine(PKA)HMM predict
955Phosphoserine(CAMK2)HMM predict
955Phosphoserine(PKG)HMM predict
956Phosphotyrosine(PKG)HMM predict
958Phosphoserine(ATM)HMM predict
965Phosphoserine(CDC2)HMM predict
982Phosphothreonine(MAPK)HMM predict
1065Phosphotyrosine(Syk)HMM predict
1158Phosphoserine(CDC2)HMM predict
1217Phosphoserine(PKG)HMM predict
1217Phosphoserine(PKA)HMM predict
1228Phosphotyrosine(INSR)HMM predict
1480N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017434
  • Location:chr15 43209483-43245065
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 43242630 43242877 247 0
CTCF CD4SISSRdata 43242630 43242877 247 0
CTCF HelaGSE12889 43242597 43242803 206 0
CTCF G2GSE9613 43214716 43215737 1021 0
CTCF G2GSE9613 43220128 43220388 260 0
CTCF G2GSE9613 43229821 43229981 160 0
CTCF G2GSE9613 43242481 43243273 792 0
Oct1 HelaGSE14283 43214091 43214130 39 0
TFAP2C MCF7GSE21234 43237574 43237815 241 0
hScc1 BcellGSE12603 43214493 43215616 1123 0
hScc1 BcellGSE12603 43218659 43218879 220 0
hScc1 BcellGSE12603 43240331 43240587 256 0
hScc1 BcellGSE12603 43240993 43241401 408 0
hScc1 BcellGSE12603 43242334 43243159 825 0
hScc1 CdLSGSE12603 43242481 43242873 392 0
p63 keratinocytesGSE17611 43241918 43242971 1053 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018