AutismKB 2.0

Annotation Detail for CPSF2


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Basic Information Top
Gene Symbol:CPSF2 ( CPSF100,KIAA1367 )
Gene Full Name: cleavage and polyadenylation specific factor 2, 100kDa
Band: 14q32.12
Quick LinksEntrez ID:53981; OMIM: 606028; Uniprot ID:CPSF2_HUMAN; ENSEMBL ID: ENSG00000165934; HGNC ID: 2325
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
395Phosphotyrosine.
412Phosphoserine (By similarity).
419Phosphoserine.
420Phosphoserine.
423Phosphoserine.
660Phosphoserine.
Location(AA) Modifications Resource
395Phosphotyrosine.Swiss-Prot 53.0
395PhosphotyrosinePhospho.ELM 6.0
419Phosphoserine.Swiss-Prot 53.0
419PhosphoserinePhospho.ELM 6.0
420Phosphoserine.Swiss-Prot 53.0
420PhosphoserinePhospho.ELM 6.0
423PhosphoserinePhospho.ELM 6.0
423Phosphoserine.Swiss-Prot 53.0
660Phosphoserine.Swiss-Prot 53.0
660PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
204N-linkedHMM predict
280Phosphoserine(CK1)HMM predict
377Phosphothreonine(CK2)HMM predict
395Phosphotyrosine(EGFR)HMM predict
419Phosphoserine(CK1)HMM predict
419Phosphoserine(CK2)HMM predict
423Phosphoserine(CK2)HMM predict
493Phosphothreonine(CK2)HMM predict
498Phosphoserine(CK1)HMM predict
601Phosphoserine(CK1)HMM predict
613Phosphoserine(IKK)HMM predict
668Phosphoserine(CK1)HMM predict
771IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017437
  • Location:chr14 91658081-91700295
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T30-glioblastomaGSE21026 91657427 91658726 1299 5
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Sox2 hESGSE18292 91700615 91700800 185 412
p63 keratinocytesGSE17611 91712388 91713016 628 12407
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 91671475 91671677 202 0
CTCF CD4SISSRdata 91671475 91671677 202 0
H3K4me3 colorectalcancer 91658464 91658857 393 0
H3ac HepG2E 91658325 91659094 769 0
H3ac HepG2E 91659796 91660615 819 0
Rb QuiescentGSE19898 91657695 91658596 901 0
TAF HelaGSE8489 91664592 91665173 581 0
TAF k562GSE8489 91659796 91660711 915 0
hScc1 CdLSGSE12603 91671339 91671756 417 0
p130 QuiescentGSE19898 91658123 91658749 626 0
p130 SenescentGSE19898 91658107 91658694 587 0
p130 shRbQuiescentGSE19898 91657820 91658595 775 0
p130 shRbSenescentGSE19898 91657954 91658781 827 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018