AutismKB 2.0

Annotation Detail for TLR9


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Basic Information Top
Gene Symbol:TLR9 ( CD289 )
Gene Full Name: toll-like receptor 9
Band: 3p21.2
Quick LinksEntrez ID:54106; OMIM: 605474; Uniprot ID:TLR9_HUMAN; ENSEMBL ID: ENSG00000173366; HGNC ID: 15633
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
64N-linked (GlcNAc...) (Potential).
129N-linked (GlcNAc...) (Potential).
200N-linked (GlcNAc...) (Potential).
210N-linked (GlcNAc...) (Potential).
242N-linked (GlcNAc...) (Potential).
300N-linked (GlcNAc...) (Potential).
340N-linked (GlcNAc...) (Potential).
469N-linked (GlcNAc...) (Potential).
474N-linked (GlcNAc...) (Potential).
513N-linked (GlcNAc...) (Potential).
567N-linked (GlcNAc...) (Potential).
694N-linked (GlcNAc...) (Potential).
731N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
64N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
129N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
200N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
210N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
242N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
300N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
340N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
469N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
474N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
513N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
567N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
694N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
731N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
12Phosphoserine(MAPK)HMM predict
64N-linkedHMM predict
71Phosphoserine(CK1)HMM predict
180Phosphotyrosine(Syk)HMM predict
200N-linkedHMM predict
210N-linkedHMM predict
242N-linkedHMM predict
295Phosphoserine(CK1)HMM predict
300N-linkedHMM predict
419Phosphotyrosine(Jak)HMM predict
428Phosphoserine(CK2)HMM predict
460Phosphothreonine(CDK)HMM predict
460Phosphothreonine(MAPK)HMM predict
469N-linkedHMM predict
474N-linkedHMM predict
513N-linkedHMM predict
576Phosphothreonine(PKC)HMM predict
664Phosphotyrosine(Syk)HMM predict
694N-linkedHMM predict
739Phosphothreonine(PKC)HMM predict
972Phosphoserine(CDC2)HMM predict
1026CysteineHMM predict
1028GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017442
  • Location:chr3 52230137-52235218
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 52234421 52236728 2307 356
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52229454 52229855 401 483
CTCF CD4SISSRdata 52229454 52229855 401 483
CTCF HelaGSE12889 52229529 52229741 212 503
CTCF G2GSE9613 52227411 52227981 570 2442
TFAP2C MCF7GSE21234 52229474 52230137 663 332
hScc1 CdLSGSE12603 52229475 52229936 461 432
hScc1 G2GSE9613 52229475 52230019 544 391
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 52229475 52231069 1594 0
CTCF G2GSE9613 52231419 52232286 867 0
CTCF G2GSE9613 52232595 52234090 1495 0
CTCF G2GSE9613 52234702 52235594 892 0
hScc1 BcellGSE12603 52229475 52231069 1594 0
hScc1 BcellGSE12603 52233753 52234090 337 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-148a hsa-mir-148a 7 21068402
hsa-miR-148a* hsa-mir-148a 7 21068402
hsa-miR-148b hsa-mir-148b 12 21068402
hsa-miR-148b* hsa-mir-148b 12 21068402
hsa-miR-152 hsa-mir-152 17 21068402
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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