AutismKB 2.0

Annotation Detail for KCNK10


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Basic Information Top
Gene Symbol:KCNK10 ( FLJ43399,K2p10.1,TREK-2,TREK2 )
Gene Full Name: potassium channel, subfamily K, member 10
Band: 14q31.3
Quick LinksEntrez ID:54207; OMIM: 605873; Uniprot ID:KCNKA_HUMAN; ENSEMBL ID: ENSG00000100433; HGNC ID: 6273
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
144N-linked (GlcNAc...) (Potential).
147N-linked (GlcNAc...) (Potential).
148N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
144N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
147N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
148N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
38Phosphothreonine(MAPK)HMM predict
38O-linkedHMM predict
38O-linkedHMM predict
38O-linkedHMM predict
40Phosphothreonine(MAPK)HMM predict
40O-linkedHMM predict
40O-linkedHMM predict
46O-linkedHMM predict
50Phosphothreonine(PKC)HMM predict
65Phosphothreonine(PKC)HMM predict
99Phosphoserine(CDK)HMM predict
147N-linkedHMM predict
148N-linkedHMM predict
149Phosphoserine(CK1)HMM predict
346N-linkedHMM predict
354Phosphothreonine(PKC)HMM predict
359Phosphoserine(PKA)HMM predict
359Phosphoserine(PKG)HMM predict
371Phosphothreonine(PKC)HMM predict
388Phosphoserine(CAMK2)HMM predict
405Phosphothreonine(PKC)HMM predict
412Phosphoserine(ATM)HMM predict
454Phosphothreonine(PKC)HMM predict
530N-linkedHMM predict
531N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021161
  • Location:chr14 87721005-87863003
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 87882076 87882501 425 19285
H3K27me3 colorectalcancer 87863175 87864157 982 663
NRSF JurkatGSE13047 87871286 87871747 461 8513
NRSF mAbJurkat 87867320 87868079 759 4696
NRSF mAbJurkat 87869484 87869891 407 6684
NRSF mAbJurkat 87870514 87871838 1324 8173
NRSF mAbJurkat 87873105 87873514 409 10306
NRSF-mono JurkatQuESTdata 87871339 87871746 407 8539
NRSF-poly JurkatQuESTdata 87871318 87871621 303 8466
RARA MCF7GSE15244 87882146 87882501 355 19320
RARG MCF7GSE15244 87882182 87882501 319 19338
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 87859363 87859681 318 0
H3K27me3 colorectalcancer 87860859 87862629 1770 0
Oct1 HelaGSE14283 87860145 87860172 27 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018