Annotation Detail for POLD2
Basic Information Top
| Gene Symbol: | POLD2 ( - ) |
|---|---|
| Gene Full Name: | polymerase (DNA directed), delta 2, regulatory subunit 50kDa |
| Band: | 7p13 |
| Quick Links | Entrez ID:5425; OMIM: 600815; Uniprot ID:DPOD2_HUMAN; ENSEMBL ID: ENSG00000106628; HGNC ID: 9176 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 1 | N-acetylmethionine. | |
| Location(AA) | Modifications | Resource |
|---|
| Location(AA) | Modification | Resource |
|---|---|---|
| 21 | N-linked | HMM predict |
| 34 | N-linked | HMM predict |
| 289 | Phosphoserine(ATM) | HMM predict |
| 303 | N-linked | HMM predict |
| 304 | Phosphotyrosine(INSR) | HMM predict |
- RefSeq ID: NM_006230
- Location:chr7 44120811-44129654
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 44129440 | 44129900 | 460 | 16 |
| CTCF | G2 | GSE9613 | 44134483 | 44135623 | 1140 | 5399 |
| Fos | K562 | GSE19551 | 44129293 | 44130059 | 766 | 22 |
| PHF8 | HeLa | GSE20725 | 44128969 | 44130643 | 1674 | 152 |
| Rb | Quiescent | GSE19898 | 44129397 | 44130021 | 624 | 55 |
| hScc1 | Bcell | GSE12603 | 44129440 | 44129900 | 460 | 16 |
| p130 | Quiescent | GSE19898 | 44129883 | 44130175 | 292 | 375 |
| p130 | Senescent | GSE19898 | 44129950 | 44130311 | 361 | 476 |
| p130 | shRbQuiescent | GSE19898 | 44129740 | 44130430 | 690 | 431 |
| p130 | shRbSenescent | GSE19898 | 44129966 | 44130581 | 615 | 619 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 44123511 | 44124108 | 597 | 0 |
| CTCF | G2 | GSE9613 | 44125358 | 44126505 | 1147 | 0 |
| CTCF | G2 | GSE9613 | 44127555 | 44127702 | 147 | 0 |
| H3ac | HepG2 | E | 44128256 | 44129055 | 799 | 0 |
| Myc | K562 | GSE19551 | 44129095 | 44130126 | 1031 | 0 |
| TAF | Hela | GSE8489 | 44128256 | 44129023 | 767 | 0 |
| p130 | Senescent | GSE19898 | 44129323 | 44129865 | 542 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 880 | Unknown | pSILAC | let-7b | POLD2 | down 50-25% | 18668040 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000106628 | n_a | n_a | n_a | "squamous cell, epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma" |
Cis-Nats regulation