AutismKB 2.0

Annotation Detail for NLGN3


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Basic Information Top
Gene Symbol:NLGN3 ( HNL3,KIAA1480 )
Gene Full Name: neuroligin 3
Band: Xq13.1
Quick LinksEntrez ID:54413; OMIM: 300336; Uniprot ID:NLGN3_HUMAN; ENSEMBL ID: ENSG00000196338; HGNC ID: 14289
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
98N-linked (GlcNAc...) (Potential).
545N-linked (GlcNAc...) (Potential).
792Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
98N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
545N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
13Phosphoserine(ATM)HMM predict
13Phosphoserine(CDC2)HMM predict
13Phosphoserine(CDK)HMM predict
13O-linkedHMM predict
17Phosphothreonine(PKC)HMM predict
43O-linkedHMM predict
74Phosphotyrosine(Abl)HMM predict
98N-linkedHMM predict
143Phosphotyrosine(Syk)HMM predict
316Phosphoserine(IKK)HMM predict
356Phosphoserine(PKG)HMM predict
431Phosphotyrosine(Jak)HMM predict
441Phosphotyrosine(Abl)HMM predict
443SulfotyrosineHMM predict
449Phosphothreonine(PKC)HMM predict
473Phosphothreonine(PKA)HMM predict
473Phosphothreonine(PKC)HMM predict
644O-linkedHMM predict
653O-linkedHMM predict
675Phosphoserine(MAPK)HMM predict
705Phosphoserine(IKK)HMM predict
711O-linkedHMM predict
748MethylarginineHMM predict
795Phosphothreonine(PKC)HMM predict
835N-linkedHMM predict
844Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018977
  • Location:chrX 70281435-70307773
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 70280862 70281077 215 466
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 70315490 70315930 440 7937
CTCF CD4SISSRdata 70315490 70315930 440 7937
CTCF HelaGSE12889 70315584 70315811 227 7924
CTCF G2GSE9613 70315510 70315909 399 7936
CTCF G2GSE9613 70318663 70319091 428 11104
CTCF G2GSE9613 70321357 70321678 321 13744
Fos K562GSE19551 70318366 70319149 783 10984
H3ac HepG2E 70319296 70319894 598 11822
H3ac HepG2E 70320693 70321749 1056 13448
Myc K562GSE19551 70318037 70319010 973 10750
Oct1 HelaGSE14283 70315098 70315134 36 7343
Oct1 HelaGSE14283 70315585 70315650 65 7844
P300 T0-glioblastomaGSE21026 70318364 70318951 587 10884
P300 T30-glioblastomaGSE21026 70318148 70319518 1370 11060
PolII HeLaGSE12783 70317868 70319414 1546 10868
TAF k562GSE8489 70318085 70318929 844 10734
USF1 HepG2E 70318008 70318848 840 10655
hScc1 BcellGSE12603 70315510 70315832 322 7898
hScc1 BcellGSE12603 70318555 70318929 374 10969
hScc1 CdLSGSE12603 70315510 70315909 399 7936
hScc1 G2GSE9613 70315510 70315909 399 7936
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 70281324 70281775 451 0
CTCF G2GSE9613 70283850 70284784 934 0
CTCF G2GSE9613 70288224 70288407 183 0
CTCF G2GSE9613 70290010 70290410 400 0
CTCF G2GSE9613 70290691 70290943 252 0
CTCF G2GSE9613 70303626 70304052 426 0
CTCF G2GSE9613 70306214 70306929 715 0
Oct1 HelaGSE14283 70294862 70294891 29 0
hScc1 BcellGSE12603 70285599 70285885 286 0
hScc1 G2GSE9613 70281353 70281648 295 0
hScc1 G2GSE9613 70306144 70306929 785 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-181b hsa-mir-181b-1 1 20868653
hsa-miR-181b hsa-mir-181b-2 9 20868653
hsa-miR-486-3p hsa-mir-486 8 20868653
hsa-miR-486-5p hsa-mir-486 8 20868653
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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