AutismKB 2.0

Annotation Detail for SH3TC1


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Basic Information Top
Gene Symbol:SH3TC1 ( FLJ20356,FLJ32999,FLJ36243,FLJ46394 )
Gene Full Name: SH3 domain and tetratricopeptide repeats 1
Band: 4p16.1
Quick LinksEntrez ID:54436; OMIM: NA; Uniprot ID:S3TC1_HUMAN; ENSEMBL ID: ENSG00000125089; HGNC ID: 26009
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1248Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
23O-linkedHMM predict
72Phosphothreonine(CDK)HMM predict
72Phosphothreonine(MAPK)HMM predict
241Phosphoserine(PKG)HMM predict
254Phosphoserine(IKK)HMM predict
255Phosphoserine(IKK)HMM predict
255Phosphoserine(CDK)HMM predict
255Phosphoserine(ATM)HMM predict
255O-linkedHMM predict
255Phosphoserine(CDC2)HMM predict
258Phosphoserine(ATM)HMM predict
258Phosphoserine(MAPK)HMM predict
258Phosphoserine(CDC2)HMM predict
260Phosphoserine(CK2)HMM predict
262O-linkedHMM predict
262O-linkedHMM predict
263Phosphoserine(CK1)HMM predict
404Phosphoserine(PKB)HMM predict
404Phosphoserine(PKA)HMM predict
436Phosphoserine(MAPK)HMM predict
436Phosphoserine(CDC2)HMM predict
436O-linkedHMM predict
442Phosphothreonine(PKC)HMM predict
476Phosphoserine(IKK)HMM predict
570S-palmitoylHMM predict
760Phosphoserine(IKK)HMM predict
777Phosphothreonine(MAPK)HMM predict
887Phosphotyrosine(EGFR)HMM predict
1092Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018986
  • Location:chr4 8251993-8293727
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 8245411 8245606 195 6485
CTCF CD4SISSRdata 8245411 8245606 195 6485
CTCF G2GSE9613 8232390 8232718 328 19440
CTCF G2GSE9613 8234230 8236188 1958 16785
CTCF G2GSE9613 8240731 8242841 2110 10208
CTCF G2GSE9613 8243569 8243979 410 8220
CTCF G2GSE9613 8245435 8246310 875 6121
CTCF G2GSE9613 8246581 8247001 420 5203
CTCF G2GSE9613 8248080 8249583 1503 3162
CTCF G2GSE9613 8250036 8250214 178 1869
ER MCF7GSE19013 8234094 8234910 816 17492
ER MCF7GSE19013 8235713 8236590 877 15842
Fos K562GSE19551 8243819 8244542 723 7813
P300 T30-glioblastomaGSE21026 8243671 8244544 873 7886
P300 T30-glioblastomaGSE21026 8251453 8252241 788 147
TFAP2C MCF7GSE21234 8235498 8236555 1057 15967
TFAP2C MCF7GSE21234 8246828 8247794 966 4683
VDR GM10855-stimGSE22484 8250954 8252339 1385 347
hScc1 BcellGSE12603 8240731 8240914 183 11171
hScc1 BcellGSE12603 8245435 8245801 366 6376
hScc1 BcellGSE12603 8250990 8251193 203 902
p130 SenescentGSE19898 8251507 8251883 376 299
p63 keratinocytesGSE17611 8241132 8242243 1111 10306
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 8294831 8295065 234 1221
CTCF CD4SISSRdata 8294831 8295065 234 1221
CTCF G2GSE9613 8294420 8295571 1151 1268
CTCF G2GSE9613 8296711 8297088 377 3172
CTCF G2GSE9613 8297682 8298201 519 4214
CTCF G2GSE9613 8299586 8300753 1167 6442
CTCF G2GSE9613 8304189 8304550 361 10642
CTCF G2GSE9613 8305117 8305421 304 11542
CTCF G2GSE9613 8305838 8306005 167 12194
Gata2 K562GSE18868 8305135 8305794 659 11737
TFAP2C MCF7GSE21234 8294905 8295183 278 1317
hScc1 BcellGSE12603 8294260 8295571 1311 1188
hScc1 BcellGSE12603 8299586 8300302 716 6217
hScc1 G2GSE9613 8296711 8297088 377 3172
hScc1 G2GSE9613 8297682 8298201 519 4214
hScc1 G2GSE9613 8299586 8300716 1130 6424
p130 SenescentGSE19898 8295073 8295222 149 1420
p63 keratinocytesGSE17611 8306505 8307397 892 13224
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 8269837 8272263 2426 0
CBP JurkatGSE17954 8276528 8283613 7085 0
CBP T30-glioblastomaGSE21026 8280953 8281569 616 0
CTCF G2GSE9613 8251369 8253301 1932 0
CTCF G2GSE9613 8253716 8254307 591 0
CTCF G2GSE9613 8254640 8255061 421 0
CTCF G2GSE9613 8256552 8258688 2136 0
CTCF G2GSE9613 8261488 8261734 246 0
CTCF G2GSE9613 8262645 8263091 446 0
CTCF G2GSE9613 8263401 8263601 200 0
CTCF G2GSE9613 8264912 8265939 1027 0
CTCF G2GSE9613 8268164 8269150 986 0
CTCF G2GSE9613 8269482 8269769 287 0
CTCF G2GSE9613 8270124 8270890 766 0
CTCF G2GSE9613 8272823 8272976 153 0
CTCF G2GSE9613 8276923 8278114 1191 0
CTCF G2GSE9613 8279470 8279734 264 0
CTCF G2GSE9613 8280326 8282305 1979 0
CTCF G2GSE9613 8284257 8285914 1657 0
CTCF G2GSE9613 8288744 8289832 1088 0
CTCF G2GSE9613 8290474 8291849 1375 0
CTCF G2GSE9613 8292244 8292587 343 0
CTCF G2GSE9613 8292839 8293500 661 0
ER MCF7GSE19013 8284791 8285406 615 0
H3ac HepG2E 8253716 8254056 340 0
NFkBII GM12878GSE19485 8251211 8255031 3820 0
NFkBII GM12878GSE19485 8280780 8282327 1547 0
NFkBII GM12892GSE19485 8251047 8252951 1904 0
NFkBII GM18526GSE19485 8250665 8255405 4740 0
NFkBII GM18526GSE19485 8280691 8282387 1696 0
Oct1 HelaGSE14283 8291910 8291943 33 0
P300 T30-glioblastomaGSE21026 8281123 8281615 492 0
Rb shRbSenescenceGSE19898 8268871 8269018 147 0
VDR GM10855-stimGSE22484 8280449 8283573 3124 0
VDR GM10861-UnstimGSE22484 8280718 8282313 1595 0
VDR GM10861-stimGSE22484 8280275 8283379 3104 0
hScc1 BcellGSE12603 8251720 8252454 734 0
hScc1 BcellGSE12603 8252783 8253301 518 0
hScc1 BcellGSE12603 8253716 8253982 266 0
hScc1 BcellGSE12603 8254420 8254822 402 0
hScc1 BcellGSE12603 8256404 8256949 545 0
hScc1 BcellGSE12603 8262197 8262714 517 0
hScc1 BcellGSE12603 8268127 8268860 733 0
hScc1 BcellGSE12603 8277415 8278263 848 0
hScc1 BcellGSE12603 8280397 8281705 1308 0
hScc1 BcellGSE12603 8290908 8291452 544 0
hScc1 G2GSE9613 8264672 8265939 1267 0
hScc1 G2GSE9613 8288709 8289405 696 0
hScc1 G2GSE9613 8290908 8291849 941 0
p63 keratinocytesGSE17611 8258399 8259509 1110 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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