AutismKB 2.0

Annotation Detail for FBXW5


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Basic Information Top
Gene Symbol:FBXW5 ( DKFZp434B205,Fbw5,MGC20962,RP11-229P13.10 )
Gene Full Name: F-box and WD repeat domain containing 5
Band: 9q34.3
Quick LinksEntrez ID:54461; OMIM: 609072; Uniprot ID:FBXW5_HUMAN; ENSEMBL ID: ENSG00000159069; HGNC ID: 13613
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
87Phosphothreonine(PKC)HMM predict
137N-linkedHMM predict
164N-linkedHMM predict
167O-linkedHMM predict
167Phosphoserine(CK1)HMM predict
229Phosphoserine(CK1)HMM predict
245N-linkedHMM predict
262Phosphoserine(IKK)HMM predict
275Phosphoserine(CDC2)HMM predict
344Phosphothreonine(PKC)HMM predict
376Phosphothreonine(PKA)HMM predict
494SulfotyrosineHMM predict
519Phosphoserine(CDC2)HMM predict
556ThreonineHMM predict
565ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018998
  • Location:chr9 138954708-138958993
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 138958977 138959284 307 137
CTCF CD4SISSRdata 138958977 138959284 307 137
ETS1 JurkatGSE17954 138958472 138959547 1075 16
VDR GM10855-UnstimGSE22484 138958408 138959779 1371 100
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 HeLaGSE20725 138954456 138959420 4964 0
PHF8 Hs68minusFBSGSE20725 138958232 138959035 803 0
PHF8 Hs68plusFBSGSE20725 138958077 138959366 1289 0
VDR GM10855-stimGSE22484 138957650 138959578 1928 0
hScc1 BcellGSE12603 138957413 138957872 459 0
p130 shRbSenescentGSE19898 138958119 138958407 288 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018