AutismKB 2.0

Annotation Detail for ROBO4


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Basic Information Top
Gene Symbol:ROBO4 ( ECSM4,FLJ20798,MGC133352,MGC133353,MRB )
Gene Full Name: roundabout homolog 4, magic roundabout (Drosophila)
Band: 11q24.2
Quick LinksEntrez ID:54538; OMIM: 607528; Uniprot ID:ROBO4_HUMAN; ENSEMBL ID: ENSG00000154133; HGNC ID: 17985
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
246N-linked (GlcNAc...).
360N-linked (GlcNAc...) (Potential).
389N-linked (GlcNAc...) (Potential).
396N-linked (GlcNAc...) (Potential).
680N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
246N-linked (GlcNAc...).Swiss-Prot 53.0
360N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
389N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
396N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
680N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
52Phosphoserine(IKK)HMM predict
62Phosphothreonine(PKC)HMM predict
112Phosphotyrosine(INSR)HMM predict
131Phosphoserine(PKG)HMM predict
205Phosphotyrosine(INSR)HMM predict
205Phosphotyrosine(SRC)HMM predict
224Phosphoserine(PKG)HMM predict
231Phosphotyrosine(EGFR)HMM predict
231Phosphotyrosine(Syk)HMM predict
231Phosphotyrosine(INSR)HMM predict
231Phosphotyrosine(Abl)HMM predict
246N-linkedHMM predict
251N-linkedHMM predict
329MethylarginineHMM predict
360N-linkedHMM predict
389N-linkedHMM predict
396N-linkedHMM predict
464Phosphothreonine(PKC)HMM predict
488S-palmitoylHMM predict
535Phosphoserine(PKA)HMM predict
539Phosphoserine(CK2)HMM predict
539Phosphoserine(IKK)HMM predict
539Phosphoserine(CK1)HMM predict
569Phosphoserine(CDC2)HMM predict
580PhosphothreonineHMM predict
593Phosphothreonine(CDC2)HMM predict
598Phosphoserine(CDK)HMM predict
598O-linkedHMM predict
598Phosphoserine(CDC2)HMM predict
615O-linkedHMM predict
616Phosphoserine(IKK)HMM predict
620Phosphoserine(CK1)HMM predict
623Phosphoserine(PKA)HMM predict
623Phosphoserine(IKK)HMM predict
631PhosphoserineHMM predict
632Phosphoserine(CDC2)HMM predict
632Phosphoserine(CDK)HMM predict
636Phosphoserine(PKG)HMM predict
680N-linkedHMM predict
682Phosphoserine(ATM)HMM predict
684Phosphoserine(CDC2)HMM predict
684Phosphoserine(CDK)HMM predict
729O-linkedHMM predict
758O-linkedHMM predict
758Phosphoserine(MAPK)HMM predict
758Phosphoserine(ATM)HMM predict
766Phosphoserine(IKK)HMM predict
768Phosphoserine(ATM)HMM predict
768Phosphoserine(CK1)HMM predict
768O-linkedHMM predict
768Phosphoserine(IKK)HMM predict
771Phosphoserine(CDC2)HMM predict
778Phosphoserine(CK1)HMM predict
781Phosphoserine(CK1)HMM predict
783Phosphoserine(CK1)HMM predict
784Phosphoserine(CK1)HMM predict
791Phosphoserine(IKK)HMM predict
794Phosphothreonine(MAPK)HMM predict
810Phosphothreonine(MAPK)HMM predict
814Phosphoserine(PKG)HMM predict
816O-linkedHMM predict
823O-linkedHMM predict
823Phosphoserine(CDC2)HMM predict
823Phosphoserine(IKK)HMM predict
827O-linkedHMM predict
828Phosphotyrosine(SRC)HMM predict
828Phosphotyrosine(Abl)HMM predict
830Phosphotyrosine(Jak)HMM predict
858S-palmitoylHMM predict
865Phosphothreonine(MAPK)HMM predict
867Phosphothreonine(CDK)HMM predict
891Phosphoserine(IKK)HMM predict
891Phosphoserine(PKG)HMM predict
891O-linkedHMM predict
896Phosphoserine(ATM)HMM predict
899Phosphoserine(IKK)HMM predict
934O-linkedHMM predict
935Phosphoserine(CDK)HMM predict
935Phosphoserine(IKK)HMM predict
935Phosphoserine(ATM)HMM predict
938Phosphoserine(CDC2)HMM predict
948N-linkedHMM predict
990Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_019055
  • Location:chr11 124259324-124272950
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Stat6 IL-4-hr4GSE17850 124275442 124276029 587 2785
hScc1 BcellGSE12603 124273859 124274064 205 1011
p130 QuiescentGSE19898 124273857 124274139 282 1048
p130 shRbQuiescentGSE19898 124273821 124274206 385 1063
p130 shRbQuiescentGSE19898 124275345 124276260 915 2852
p130 shRbSenescentGSE19898 124273824 124274098 274 1011
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 124262729 124263003 274 0
NRSF pAbJurkat 124269140 124269481 341 0
NRSF pAbJurkat 124272344 124272877 533 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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