AutismKB 2.0

Annotation Detail for DDIT4


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Basic Information Top
Gene Symbol:DDIT4 ( Dig2,FLJ20500,REDD-1,REDD1,RP11-442H21.1,RTP801 )
Gene Full Name: DNA-damage-inducible transcript 4
Band: 10q22.1
Quick LinksEntrez ID:54541; OMIM: 607729; Uniprot ID:DDIT4_HUMAN; ENSEMBL ID: ENSG00000168209; HGNC ID: 24944
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_019058
  • Location:chr10 73703682-73705802
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 73702041 73704302 2261 511
H3ac HepG2E 73684455 73685438 983 18736
H3ac HepG2E 73686769 73687302 533 16647
H3ac HepG2E 73691115 73691493 378 12379
H3ac HepG2E 73702104 73702539 435 1361
HIF1 HypoHepG2 73690344 73691493 1149 12764
HIF1 HypoHepG2 73703264 73703992 728 55
NFkBII GM12878GSE19485 73688791 73691931 3140 13322
NFkBII GM12892GSE19485 73686577 73687665 1088 16562
Nanog hESGSE18292 73697144 73697491 347 6365
Oct1 HelaGSE14283 73687232 73687273 41 16430
RARA MCF7GSE15244 73689677 73690378 701 13655
RARA MCF7GSE15244 73702177 73702924 747 1132
RARG MCF7GSE15244 73689677 73690378 701 13655
RARG MCF7GSE15244 73701888 73702895 1007 1291
Rb GrowingGSE19898 73690518 73690754 236 13047
Rb SenescentGSE19898 73689617 73689896 279 13926
Rb SenescentGSE19898 73690239 73690694 455 13216
TAF k562GSE8489 73701888 73702279 391 1599
TFAP2C MCF7GSE21234 73690087 73690826 739 13226
TFAP2C MCF7GSE21234 73701765 73703187 1422 1207
TFAP2C MCF7GSE21234 73703219 73703502 283 322
hScc1 BcellGSE12603 73690633 73691493 860 12620
hScc1 CdLSGSE12603 73691115 73691493 378 12379
p130 QuiescentGSE19898 73684701 73684938 237 18863
p130 shRbQuiescentGSE19898 73702205 73703295 1090 933
p130 shRbSenescentGSE19898 73690451 73690966 515 12974
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 73720522 73721376 854 15147
USF1 HepG2E 73725019 73725584 565 19499
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 73704795 73705809 1014 0
Pol2 GM12878GSE19551 73702230 73707392 5162 0
TAF k562GSE8489 73704509 73705698 1189 0
USF2 HepG2E 73704995 73705734 739 0
VDR GM10861-stimGSE22484 73702085 73707827 5742 0
hScc1 BcellGSE12603 73703562 73704239 677 0
hScc1 BcellGSE12603 73704581 73704859 278 0
hScc1 CdLSGSE12603 73703355 73704968 1613 0
p130 SenescentGSE19898 73703437 73704036 599 0
p130 shRbQuiescentGSE19898 73703478 73703925 447 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7c hsa-let-7c 21 20018759
hsa-let-7c* hsa-let-7c 21 20018759
hsa-miR-21 hsa-mir-21 17 20018759
hsa-miR-21* hsa-mir-21 17 20018759
hsa-miR-211 hsa-mir-211 15 20018759
hsa-miR-221 hsa-mir-221 X 20018759
hsa-miR-221* hsa-mir-221 X 20018759
hsa-miR-222 hsa-mir-222 X 20018759
hsa-miR-222* hsa-mir-222 X 20018759
hsa-miR-34a hsa-mir-34a 1 20018759
hsa-miR-34a* hsa-mir-34a 1 20018759
hsa-miR-495 hsa-mir-495 14 21258409
hsa-miR-519a hsa-mir-519a-1 19 20018759
hsa-miR-519a hsa-mir-519a-2 19 20018759
hsa-miR-93 hsa-mir-93 7 20018759
hsa-miR-93* hsa-mir-93 7 20018759
hsa-miR-96 hsa-mir-96 7 20018759
hsa-miR-96* hsa-mir-96 7 20018759
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018