AutismKB 2.0

Annotation Detail for WDR74


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Basic Information Top
Gene Symbol:WDR74 ( FLJ10439,FLJ21730 )
Gene Full Name: WD repeat domain 74
Band: 11q12.3
Quick LinksEntrez ID:54663; OMIM: NA; Uniprot ID:WDR74_HUMAN; ENSEMBL ID: ENSG00000133316; HGNC ID: 25529
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
361Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
32N-linkedHMM predict
214Phosphoserine(CDC2)HMM predict
225Phosphotyrosine(SRC)HMM predict
361Phosphoserine(PKG)HMM predict
361PhosphoserineHMM predict
372Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018093
  • Location:chr11 62356959-62364203
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 62364889 62366331 1442 1407
CTCF JurkatGSE12889 62365505 62365925 420 1512
P300 T0-glioblastomaGSE21026 62365102 62366438 1336 1567
P300 T30-glioblastomaGSE21026 62363044 62366734 3690 686
PolII HeLaGSE12783 62362493 62367065 4572 576
RARG MCF7GSE15244 62365969 62366233 264 1898
p130 QuiescentGSE19898 62365406 62365803 397 1401
p130 SenescentGSE19898 62365371 62365690 319 1327
p130 shRbQuiescentGSE19898 62366236 62366916 680 2373
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb GrowingGSE19898 62356723 62356852 129 172
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 62358828 62359565 737 0
FOXA1 MCF7GSE15244 62362850 62364019 1169 0
H3K4me3 colorectalcancer 62357377 62357934 557 0
H3ac HepG2E 62356381 62358371 1990 0
H3ac HepG2E 62358977 62360793 1816 0
H3ac HepG2E 62361576 62361907 331 0
H3ac HepG2E 62362850 62364019 1169 0
Oct1 H2O2-HelaGSE14283 62357847 62357876 29 0
Oct1 HelaGSE14283 62357843 62357877 34 0
PHF8 HeLaGSE20725 62363005 62363999 994 0
RARA MCF7GSE15244 62363556 62364019 463 0
RARG MCF7GSE15244 62363451 62363954 503 0
RNAII Tamoxifen-MCF7GSE14664 62357839 62357878 39 0
RNAII Tamoxifen-MCF7GSE14664 62359493 62359583 90 0
TAF HelaGSE8489 62360087 62360793 706 0
TAF HelaGSE8489 62362850 62364019 1169 0
TAF k562GSE8489 62362850 62364019 1169 0
TAFII hESGSE17917 62363307 62363935 628 0
TFAP2C MCF7GSE21234 62363363 62363974 611 0
hScc1 BcellGSE12603 62360507 62360793 286 0
hScc1 BcellGSE12603 62363199 62364019 820 0
hScc1 CdLSGSE12603 62363271 62363632 361 0
p130 SenescentGSE19898 62363348 62364066 718 0
p130 shRbSenescentGSE19898 62363394 62363869 475 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4618 EST chr11 62356284 62358091 203 mRNA FLJ10439 chr11 62356959 62364204Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018