AutismKB 2.0

Annotation Detail for PPEF2


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Basic Information Top
Gene Symbol:PPEF2 ( PPP7CB )
Gene Full Name: protein phosphatase, EF-hand calcium binding domain 2
Band: 4q21.1
Quick LinksEntrez ID:5470; OMIM: 602256; Uniprot ID:PPE2_HUMAN; ENSEMBL ID: ENSG00000156194; HGNC ID: 9244
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
105Phosphotyrosine(INSR)HMM predict
113Phosphoserine(IKK)HMM predict
198Phosphoserine(CDK)HMM predict
198Phosphoserine(CDC2)HMM predict
324Phosphoserine(CAMK2)HMM predict
353Phosphoserine(CK1)HMM predict
353Phosphoserine(IKK)HMM predict
357Phosphoserine(CDC2)HMM predict
357Phosphoserine(CDK)HMM predict
369Phosphothreonine(PKC)HMM predict
372O-linkedHMM predict
421Phosphoserine(CAMK2)HMM predict
421Phosphoserine(PKB)HMM predict
421Phosphoserine(IKK)HMM predict
512Phosphotyrosine(Syk)HMM predict
513Phosphotyrosine(Syk)HMM predict
552Phosphoserine(PKG)HMM predict
653N-linkedHMM predict
656N-linkedHMM predict
745Phosphoserine(IKK)HMM predict
745O-linkedHMM predict
749Phosphoserine(CDC2)HMM predict
749PhosphoserineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006239
  • Location:chr4 77000051-77042704
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 76983982 76984994 1012 15564
CTCF CD4GSE12889 76988519 76988682 163 11451
CTCF CD4SISSRdata 76988519 76988682 163 11451
CTCF HelaGSE12889 76988558 76988777 219 11384
CTCF G2GSE9613 76988192 76988638 446 11637
CTCF G2GSE9613 76989696 76990077 381 10165
CTCF G2GSE9613 76993852 76994169 317 6041
FoxA1 MCF7MACSdata 76996615 76996878 263 3305
H3ac HepG2E 76982273 76982599 326 17616
Sox2 hESGSE18292 76988440 76988721 281 11471
hScc1 BcellGSE12603 76988192 76988638 446 11637
hScc1 CdLSGSE12603 76988192 76988638 446 11637
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 77026172 77026305 133 0
CTCF CD4GSE12889 77036010 77036214 204 0
CTCF CD4SISSRdata 77026172 77026305 133 0
CTCF CD4SISSRdata 77036010 77036214 204 0
CTCF G2GSE9613 77036069 77036460 391 0
Fos K562GSE19551 77026126 77026453 327 0
Jun K562GSE19551 77026156 77026454 298 0
Myc K562GSE19551 77026144 77026404 260 0
Myc K562GSE19551 77036009 77036295 286 0
Nanog ESGSE20650 77026190 77026524 334 0
Oct4 ESGSE20650 77026085 77026564 479 0
Pol3 K562GSE19551 77026080 77026381 301 0
TFAP2C MCF7GSE21234 77000774 77001108 334 0
hScc1 BcellGSE12603 77026215 77026522 307 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018