AutismKB 2.0

Annotation Detail for OTUD4


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Basic Information Top
Gene Symbol:OTUD4 ( DKFZp434I0721,DUBA6,HIN1,HSHIN1,KIAA1046 )
Gene Full Name: OTU domain containing 4
Band: 4q31.21
Quick LinksEntrez ID:54726; OMIM: 611744; Uniprot ID:OTUD4_HUMAN; ENSEMBL ID: ENSG00000164164; HGNC ID: 24949
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
438Phosphotyrosine.
442Phosphoserine.
556Phosphoserine.
940Phosphoserine.
1005Phosphoserine.
1010Phosphoserine (By similarity).
1022Phosphoserine.
1023Phosphoserine.
Location(AA) Modifications Resource
439Phosphotyrosine.Swiss-Prot 53.0
941Phosphoserine.Swiss-Prot 53.0
1023Phosphoserine.Swiss-Prot 53.0
1023PhosphoserinePhospho.ELM 6.0
1024Phosphoserine.Swiss-Prot 53.0
1024PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
57Phosphoserine(ATM)HMM predict
90Phosphotyrosine(Syk)HMM predict
124N-linkedHMM predict
199Phosphoserine(CK1)HMM predict
202Phosphoserine(CK1)HMM predict
202Phosphoserine(CK2)HMM predict
202Phosphoserine(CK2)HMM predict
211Phosphoserine(CK1)HMM predict
237N-linkedHMM predict
393Phosphoserine(CK1)HMM predict
396Phosphoserine(IKK)HMM predict
399Phosphoserine(CK1)HMM predict
399Phosphoserine(ATM)HMM predict
401Phosphoserine(ATM)HMM predict
410N-linkedHMM predict
476Phosphoserine(CK1)HMM predict
477Phosphoserine(CK1)HMM predict
479N-linkedHMM predict
483Phosphoserine(IKK)HMM predict
483Phosphoserine(ATM)HMM predict
535N-linkedHMM predict
541Phosphotyrosine(Jak)HMM predict
541Phosphotyrosine(Syk)HMM predict
543Phosphothreonine(PKC)HMM predict
546Phosphoserine(CDC2)HMM predict
546Phosphoserine(CDK)HMM predict
546Phosphoserine(CDK)HMM predict
557Phosphoserine(CDC2)HMM predict
589O-linkedHMM predict
589O-linkedHMM predict
593O-linkedHMM predict
602O-linkedHMM predict
603O-linkedHMM predict
607O-linkedHMM predict
623O-linkedHMM predict
636Phosphothreonine(MAPK)HMM predict
638Phosphoserine(CDC2)HMM predict
638O-linkedHMM predict
757N-linkedHMM predict
791O-linkedHMM predict
792Phosphoserine(CDC2)HMM predict
792Phosphoserine(CDK)HMM predict
893Phosphoserine(CK1)HMM predict
905Phosphoserine(CK1)HMM predict
905Phosphoserine(IKK)HMM predict
922Phosphoserine(CK1)HMM predict
930Phosphoserine(CK1)HMM predict
943Phosphothreonine(PKC)HMM predict
1023Phosphoserine(CK1)HMM predict
1024Phosphoserine(CK2)HMM predict
1024Phosphoserine(CK1)HMM predict
1043Phosphotyrosine(EGFR)HMM predict
1043Phosphotyrosine(Syk)HMM predict
1044N-linkedHMM predict
1069Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017493
  • Location:chr4 146299739-146315345
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 146320151 146321835 1684 5648
ETS1 JurkatGSE17954 146320650 146321971 1321 5965
H3K4me3 colorectalcancer 146318177 146320250 2073 3868
H3ac HepG2E 146318177 146320283 2106 3885
PHF8 HeLaGSE20725 146320023 146321905 1882 5619
Rb SenescentGSE19898 146320956 146321318 362 5792
Rb shRbQuiescentGSE19898 146325296 146325434 138 10020
hScc1 BcellGSE12603 146320080 146321595 1515 5492
p130 SenescentGSE19898 146321405 146321797 392 6256
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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