AutismKB 2.0

Annotation Detail for KLHL24


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Basic Information Top
Gene Symbol:KLHL24 ( DRE1,FLJ25796,KRIP6 )
Gene Full Name: kelch-like 24 (Drosophila)
Band: 3q27.1
Quick LinksEntrez ID:54800; OMIM: 611295; Uniprot ID:KLH24_HUMAN; ENSEMBL ID: ENSG00000114796; HGNC ID: 25947
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
19Phosphoserine(CDC2)HMM predict
22Phosphothreonine(PKC)HMM predict
46Phosphoserine(CK2)HMM predict
179Phosphoserine(CK1)HMM predict
199Phosphoserine(ATM)HMM predict
215Phosphotyrosine(INSR)HMM predict
309Phosphothreonine(PKA)HMM predict
335Phosphotyrosine(Syk)HMM predict
445O-linkedHMM predict
446Phosphoserine(CDK)HMM predict
446Phosphoserine(CDC2)HMM predict
446O-linkedHMM predict
547Phosphotyrosine(INSR)HMM predict
593TyrosineHMM predict
597CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017644
  • Location:chr3 184836104-184884995
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 184829603 184830044 441 6281
CTCF G2GSE9613 184832735 184833011 276 3232
Rb SenescentGSE19898 184835586 184836020 434 302
USF1 HepG2E 184835469 184836183 714 279
p130 QuiescentGSE19898 184835718 184835918 200 287
p130 SenescentGSE19898 184835705 184836274 569 115
p130 shRbQuiescentGSE19898 184835519 184836340 821 175
p130 shRbSenescentGSE19898 184835591 184836607 1016 6
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 184865014 184866182 1168 0
ETS1 JurkatGSE17954 184835512 184837828 2316 0
FOXA1 MCF7GSE15244 184865360 184865706 346 0
H3K4me3 colorectalcancer 184837697 184838095 398 0
H3ac HepG2E 184837631 184838095 464 0
P300 T0-glioblastomaGSE21026 184865025 184866285 1260 0
P300 T30-glioblastomaGSE21026 184864941 184866265 1324 0
PHF8 293TGSE20725 184835794 184836681 887 0
PHF8 HeLaGSE20725 184835519 184837755 2236 0
RARA MCF7GSE15244 184837841 184838095 254 0
Rb SenescentGSE19898 184836763 184837302 539 0
TFAP2C MCF7GSE21234 184836717 184837327 610 0
p130 SenescentGSE19898 184837099 184837448 349 0
p130 shRbSenescentGSE19898 184837014 184837278 264 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018