AutismKB 2.0

Annotation Detail for TRPM7


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Basic Information Top
Gene Symbol:TRPM7 ( CHAK,CHAK1,FLJ20117,FLJ25718,LTRPC7,TRP-PLIK )
Gene Full Name: transient receptor potential cation channel, subfamily M, member 7
Band: 15q21.2
Quick LinksEntrez ID:54822; OMIM: 605692; Uniprot ID:TRPM7_HUMAN; ENSEMBL ID: ENSG00000092439; HGNC ID: 17994
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1404Phosphoserine.
1477Phosphoserine.
1493Phosphoserine (By similarity).
Location(AA) Modifications Resource
1493Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
5Phosphoserine(IKK)HMM predict
44S-palmitoylHMM predict
92Phosphotyrosine(SRC)HMM predict
404N-linkedHMM predict
550N-linkedHMM predict
555Phosphothreonine(CDK)HMM predict
603Phosphothreonine(PKC)HMM predict
603Phosphothreonine(CK2)HMM predict
676Phosphoserine(CK2)HMM predict
715N-linkedHMM predict
718N-linkedHMM predict
788Phosphoserine(ATM)HMM predict
805N-linkedHMM predict
1049Phosphotyrosine(Abl)HMM predict
1058N-linkedHMM predict
1143S-palmitoylHMM predict
1144S-palmitoylHMM predict
1146S-palmitoylHMM predict
1191Phosphoserine(CK2)HMM predict
1227Phosphoserine(IKK)HMM predict
1230Phosphoserine(CK1)HMM predict
1350Phosphoserine(CK1)HMM predict
1361Phosphoserine(IKK)HMM predict
1390Phosphoserine(CK1)HMM predict
1404O-linkedHMM predict
1413PhosphoserineHMM predict
1413Phosphoserine(IKK)HMM predict
1446Phosphoserine(CAMK2)HMM predict
1465N-linkedHMM predict
1466N-linkedHMM predict
1470N-linkedHMM predict
1504PhosphoserineHMM predict
1504Phosphoserine(PKB)HMM predict
1504Phosphoserine(IKK)HMM predict
1504Phosphoserine(CK1)HMM predict
1504PhosphoserineHMM predict
1543Phosphoserine(CDC2)HMM predict
1554Phosphotyrosine(Syk)HMM predict
1567Phosphoserine(ATM)HMM predict
1573PhosphothreonineHMM predict
1596N-linkedHMM predict
1597N-linkedHMM predict
1602C-linkedHMM predict
1603Phosphoserine(IKK)HMM predict
1774N-linkedHMM predict
1829Phosphotyrosine(INSR)HMM predict
1842Phosphoserine(CK1)HMM predict
1850N-linkedHMM predict
1857Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017672
  • Location:chr15 48639782-48766259
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 48766458 48767068 610 504
Myc hESGSE17917 48766240 48766500 260 111
PHF8 293TGSE20725 48765653 48766956 1303 45
USF1 HepG2E 48767425 48767894 469 1400
USF2 HepG2E 48766422 48767068 646 486
p63 keratinocytesGSE17611 48765501 48767152 1651 67
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 48637026 48637053 27 2743
Oct1 HelaGSE14283 48637027 48637064 37 2737
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 48755109 48755431 322 0
CTCF CD4SISSRdata 48755109 48755431 322 0
CTCF G2GSE9613 48765707 48766494 787 0
ER E2-MCF7GSE14664 48740106 48740138 32 0
ER Fulvestrant-MCF7GSE14664 48740106 48740139 33 0
H3K4me3 colorectalcancer 48764970 48765513 543 0
H3ac HepG2E 48761788 48762360 572 0
H3ac HepG2E 48764970 48766110 1140 0
Oct1 H2O2-HelaGSE14283 48730680 48730724 44 0
Oct1 HelaGSE14283 48730681 48730712 31 0
Oct1 HelaGSE14283 48750013 48750039 26 0
PHF8 HeLaGSE20725 48765554 48766905 1351 0
PHF8 Hs68minusFBSGSE20725 48765437 48767032 1595 0
TAF HelaGSE8489 48764970 48765237 267 0
USF1 HepG2E 48764970 48767068 2098 0
USF2 HepG2E 48764970 48766110 1140 0
hScc1 BcellGSE12603 48765621 48766494 873 0
p63 keratinocytesGSE17611 48732555 48733262 707 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018