AutismKB 2.0

Annotation Detail for LIME1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LIME1 ( FLJ20406,LIME,LP8067,dJ583P15.4 )
Gene Full Name: Lck interacting transmembrane adaptor 1
Band: 20q13.33
Quick LinksEntrez ID:54923; OMIM: 609809; Uniprot ID:LIME1_HUMAN; ENSEMBL ID: ENSG00000203896; HGNC ID: 26016
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
145Phosphotyrosine (By similarity).
167Phosphotyrosine (Probable).
200Phosphotyrosine.
235Phosphotyrosine (By similarity).
254Phosphotyrosine; by LCK (Probable).
Location(AA) Modifications Resource
28S-palmitoyl cysteine (Probable).Swiss-Prot 53.0
31S-palmitoyl cysteine (Probable).Swiss-Prot 53.0
145Phosphotyrosine (By similarity).Swiss-Prot 53.0
167Phosphotyrosine (Probable).Swiss-Prot 53.0
200Phosphotyrosine (Probable).Swiss-Prot 53.0
235Phosphotyrosine (By similarity).Swiss-Prot 53.0
254Phosphotyrosine (by LCK) (Probable).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(IKK)HMM predict
118O-linkedHMM predict
157O-linkedHMM predict
161Phosphoserine(CDK)HMM predict
161Phosphoserine(CDC2)HMM predict
176Phosphothreonine(PKA)HMM predict
176Phosphothreonine(PKC)HMM predict
179Phosphoserine(CDC2)HMM predict
179Phosphoserine(CDK)HMM predict
191Phosphothreonine(PKA)HMM predict
191Phosphothreonine(MAPK)HMM predict
214O-linkedHMM predict
254Phosphotyrosine(SRC)HMM predict
254Phosphotyrosine(Syk)HMM predict
274Phosphothreonine(MAPK)HMM predict
278O-linkedHMM predict
282Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017806
  • Location:chr20 61838438-61840899
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
VDR GM10855-stimGSE22484 61837676 61840562 2886 0
hScc1 BcellGSE12603 61839112 61840917 1805 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018