Annotation Detail for PARP16

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Basic Information Top

Gene Symbol:	PARP16 ( C15orf30,FLJ20509,FLJ25281,pART15 )
Gene Full Name:	poly (ADP-ribose) polymerase family, member 16
Band:	15q22.31
Quick Links	Entrez ID:54956; OMIM: NA; Uniprot ID:PAR16_HUMAN; ENSEMBL ID: ENSG00000138617; HGNC ID: 26040
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

No data

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	63377185	63377523	338	11284
CTCF	CD4	GSE12889	63383594	63383932	338	17693
CTCF	CD4	SISSRdata	63377185	63377523	338	11284
CTCF	CD4	SISSRdata	63383594	63383932	338	17693
CTCF	G2	GSE9613	63377240	63377524	284	11312
CTCF	G2	GSE9613	63382907	63383864	957	17315
H3ac	HepG2	E	63377240	63377524	284	11312
H3ac	HepG2	E	63379129	63379548	419	13268
H3ac	HepG2	E	63383013	63383732	719	17302
Myc	hES	GSE17917	63384598	63384913	315	18685
Nanog	hES	GSE18292	63383751	63384373	622	17992
Oct4	hES	GSE21916	63366074	63366620	546	277
P300	T0-glioblastoma	GSE21026	63374979	63376289	1310	9564
P300	T30-glioblastoma	GSE21026	63374869	63376329	1460	9529
PHF8	HeLa	GSE20725	63365330	63366968	1638	79
PHF8	Hs68plusFBS	GSE20725	63375008	63376186	1178	9527
Pol2	GM12878	GSE19551	63375099	63376093	994	9526
Pol2	GM12878	GSE19551	63379519	63380090	571	13734
PolII	HeLa	GSE12783	63374800	63377831	3031	10245
PolII	HeLa	GSE12783	63382742	63385819	3077	18210
TAF	Hela	GSE8489	63383228	63383831	603	17459
hScc1	Bcell	GSE12603	63365689	63366682	993	115
hScc1	Bcell	GSE12603	63377240	63377524	284	11312
hScc1	CdLS	GSE12603	63377240	63377457	217	11278
p130	Quiescent	GSE19898	63384274	63384643	369	18388
p130	Senescent	GSE19898	63384103	63384865	762	18414
p130	shRbSenescent	GSE19898	63384268	63384941	673	18534

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	E2-MCF7	GSE14664	63326599	63326642	43	10870
NFkBII	GM12892	GSE19485	63328713	63329936	1223	8166
NFkBII	GM15510	GSE19485	63328898	63329633	735	8225
NFkBII	GM18526	GSE19485	63328705	63329662	957	8307
p63	keratinocytes	GSE17611	63325418	63326528	1110	11518

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	63350455	63350593	138
CTCF	CD4	SISSRdata	63350455	63350593	138
CTCF	G2	GSE9613	63350261	63350554	293
CTCF	G2	GSE9613	63365428	63366612	1184
ER	E2-MCF7	GSE14664	63361601	63361641	40
FOXA1	eGFP	GSE10845	63357701	63358517	816
Fos	K562	GSE19551	63354918	63355607	689
H3ac	HepG2	E	63364846	63365464	618
hScc1	Bcell	GSE12603	63350261	63350554	293

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
276	Unknown	MicroArray	miR-124	PARP16	n_a	15685193
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000138617		G1-to-S transition	n_a	n_a	lymphocyte	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018