AutismKB 2.0

Annotation Detail for PPM1G


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Basic Information Top
Gene Symbol:PPM1G ( MGC1675,MGC2870,PP2CG,PP2CGAMMA,PPP2CG )
Gene Full Name: protein phosphatase, Mg2+/Mn2+ dependent, 1G
Band: 2p23.3
Quick LinksEntrez ID:5496; OMIM: 605119; Uniprot ID:PPM1G_HUMAN; ENSEMBL ID: ENSG00000115241; HGNC ID: 9278
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
183Phosphoserine.
383N6-acetyllysine.
527Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
6Phosphoserine(ATM)HMM predict
10Phosphothreonine(PKC)HMM predict
106Phosphothreonine(PKC)HMM predict
183Phosphoserine(ATM)HMM predict
199Phosphothreonine(MAPK)HMM predict
199Phosphothreonine(CDK)HMM predict
201Phosphoserine(ATM)HMM predict
201O-linkedHMM predict
240O-linkedHMM predict
264Phosphoserine(ATM)HMM predict
264Phosphoserine(CK1)HMM predict
264Phosphoserine(CK2)HMM predict
274Phosphoserine(CK1)HMM predict
274PhosphoserineHMM predict
278Phosphoserine(CK2)HMM predict
278Phosphoserine(CK1)HMM predict
284Phosphotyrosine(SRC)HMM predict
284Phosphotyrosine(INSR)HMM predict
284Phosphotyrosine(EGFR)HMM predict
284Phosphotyrosine(Syk)HMM predict
284SulfotyrosineHMM predict
285Phosphoserine(CK2)HMM predict
285Phosphoserine(CK1)HMM predict
286PhosphoserineHMM predict
325O-linkedHMM predict
461Phosphoserine(ATM)HMM predict
497N-linkedHMM predict
527Phosphoserine(CK1)HMM predict
543AlanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002707
  • Location:chr2 27457565-27485952
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 SenescentGSE19898 27457108 27457694 586 165
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27484501 27486237 1736 0
ETS1 JurkatGSE17954 27485198 27486691 1493 0
GABP k562GSE8489 27457426 27458710 1284 0
GABP k562GSE8489 27459651 27460213 562 0
GABP k562GSE8489 27482411 27483301 890 0
GABP k562GSE8489 27484544 27485355 811 0
H3K4me3 colorectalcancer 27485072 27485458 386 0
H3ac HepG2E 27482614 27483301 687 0
Oct1 H2O2-HelaGSE14283 27485044 27485072 28 0
Oct1 HelaGSE14283 27485045 27485083 38 0
Rb GrowingGSE19898 27485269 27485498 229 0
Rb QuiescentGSE19898 27485223 27485536 313 0
Rb QuiescentGSE19898 27485838 27486051 213 0
Rb SenescentGSE19898 27485276 27485764 488 0
TAF k562GSE8489 27482411 27483301 890 0
TAF k562GSE8489 27484857 27485213 356 0
hScc1 BcellGSE12603 27484997 27486133 1136 0
hScc1 G2GSE9613 27484501 27486133 1632 0
p130 QuiescentGSE19898 27485289 27485432 143 0
p130 SenescentGSE19898 27485320 27485631 311 0
p130 shRbSenescentGSE19898 27485260 27485829 569 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018