AutismKB 2.0

Annotation Detail for HERC6


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Basic Information Top
Gene Symbol:HERC6 ( FLJ20637 )
Gene Full Name: hect domain and RLD 6
Band: 4q22.1
Quick LinksEntrez ID:55008; OMIM: 609249; Uniprot ID:HERC6_HUMAN; ENSEMBL ID: ENSG00000138642; HGNC ID: 26072
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
17Phosphothreonine(PKA)HMM predict
17Phosphothreonine(PKC)HMM predict
20Phosphoserine(CDC2)HMM predict
144Phosphoserine(CK1)HMM predict
168Phosphoserine(IKK)HMM predict
171Phosphoserine(CDC2)HMM predict
171Phosphoserine(CDK)HMM predict
177Phosphoserine(CK1)HMM predict
199S-palmitoylHMM predict
263N-linkedHMM predict
270Phosphotyrosine(Jak)HMM predict
271Phosphoserine(CDC2)HMM predict
273Phosphothreonine(CDC2)HMM predict
273Phosphothreonine(MAPK)HMM predict
273Phosphothreonine(CDK)HMM predict
319O-linkedHMM predict
320O-linkedHMM predict
320Phosphoserine(CK1)HMM predict
367Phosphoserine(CK1)HMM predict
369O-linkedHMM predict
398Phosphothreonine(PKA)HMM predict
427Phosphothreonine(PKA)HMM predict
614Phosphothreonine(CDC2)HMM predict
614Phosphothreonine(MAPK)HMM predict
652Phosphotyrosine(INSR)HMM predict
669Phosphoserine(CDC2)HMM predict
679Phosphoserine(PKG)HMM predict
690Phosphoserine(CAMK2)HMM predict
690Phosphoserine(PKG)HMM predict
733SulfotyrosineHMM predict
855Phosphotyrosine(INSR)HMM predict
855Phosphotyrosine(EGFR)HMM predict
872Phosphotyrosine(EGFR)HMM predict
906SulfotyrosineHMM predict
921Phosphotyrosine(Jak)HMM predict
994Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017912
  • Location:chr4 89518914-89583270
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 89518143 89518194 51 746
ER Fulvestrant-MCF7GSE14664 89518159 89518198 39 736
Fos K562GSE19551 89501336 89501829 493 17332
Fos K562GSE19551 89510759 89511109 350 7981
Oct1 HelaGSE14283 89518161 89518203 42 733
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 89585954 89586253 299 2833
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 89519095 89519241 146 0
CTCF CD4SISSRdata 89519095 89519241 146 0
CTCF HelaGSE12889 89519109 89519238 129 0
CTCF G2GSE9613 89518911 89519620 709 0
CTCF G2GSE9613 89538732 89538890 158 0
ER MCF7GSE19013 89551368 89552220 852 0
FoxA1 MCF7MACSdata 89551663 89551992 329 0
NFkBII GM12878GSE19485 89520795 89523845 3050 0
Oct1 H2O2-HelaGSE14283 89538021 89538061 40 0
Oct1 HelaGSE14283 89538017 89538065 48 0
TFAP2C MCF7GSE21234 89551628 89552151 523 0
TFAP2C MCF7GSE21234 89579414 89579982 568 0
hScc1 BcellGSE12603 89518911 89519756 845 0
hScc1 CdLSGSE12603 89518911 89519756 845 0
hScc1 G2GSE9613 89518911 89519620 709 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16-1* hsa-mir-16-1 13 18362358
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19957 mRNA HERC6 chr4 89657069 89721426 341 EST chr4 89656810 89657410Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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