Annotation Detail for CCDC109B

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Basic Information Top

Gene Symbol:	CCDC109B ( FLJ20647 )
Gene Full Name:	coiled-coil domain containing 109B
Band:	4q25
Quick Links	Entrez ID:55013; OMIM: NA; Uniprot ID:C109B_HUMAN; ENSEMBL ID: ENSG00000005059; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:5 results

Location(AA)	Modification
191	N6-acetyllysine.

Location(AA)	Modification	Resource
180	Phosphoserine(ATM)	HMM predict
276	Phosphotyrosine(Jak)	HMM predict
315	Phosphoserine(PKG)	HMM predict
319	Alanine	HMM predict
322	Phosphoserine(IKK)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_017918
Location:chr4 110700865-110828316
strand:+

Upstream the gene:8 results
Downstream the gene:0 results
Inside the gene:16 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Rb	Growing	GSE19898	110700595	110700738	143	199
Rb	Senescent	GSE19898	110700576	110700954	378	101
Rb	shRbSenescence	GSE19898	110700716	110701001	285	7
hScc1	CdLS	GSE12603	110700561	110701114	553	28
p130	Quiescent	GSE19898	110700282	110700630	348	410
p130	Senescent	GSE19898	110700446	110700855	409	215
p130	shRbQuiescent	GSE19898	110700308	110700691	383	366
p130	shRbSenescent	GSE19898	110700532	110700951	419	124

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	110715077	110715375	298	0
CTCF	CD4	GSE12889	110799612	110799762	150	0
CTCF	CD4	SISSRdata	110715077	110715375	298	0
CTCF	CD4	SISSRdata	110799612	110799762	150	0
CTCF	G2	GSE9613	110700716	110701648	932	0
CTCF	G2	GSE9613	110804309	110804562	253	0
FoxA1	MCF7	MACSdata	110701582	110701764	182	0
Myc	hES	GSE17917	110700976	110701364	388	0
Nanog	ES	GSE20650	110757533	110758195	662	0
Oct1	H2O2-Hela	GSE14283	110731046	110731075	29	0
Oct1	Hela	GSE14283	110731043	110731079	36	0
TFAP2C	MCF7	GSE21234	110729606	110730238	632	0
hScc1	Bcell	GSE12603	110700383	110701837	1454	0
hScc1	G2	GSE9613	110700790	110701648	858	0
p130	shRbSenescent	GSE19898	110717234	110717424	190	0
p63	keratinocytes	GSE17611	110735729	110736387	658	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
20064	mRNA	FLJ20647	chr4	110839051	110967478	90	mRNA	CASP6	chr4	110967388	110982233	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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