AutismKB 2.0

Annotation Detail for PPP1R3A


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Basic Information Top
Gene Symbol:PPP1R3A ( GM,PP1G,PPP1R3 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 3A
Band: 7q31.1
Quick LinksEntrez ID:5506; OMIM: 600917; Uniprot ID:PPR3A_HUMAN; ENSEMBL ID: ENSG00000154415; HGNC ID: 9291
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
38Phosphoserine; by GSK3 (By similarity).
42Phosphoserine; by GSK3 (By similarity).
46Phosphoserine; by PKA and ISPK (By
65Phosphoserine; by PKA (By similarity).
65PP1-binding motif.
261Phosphoserine (By similarity).
759Phosphothreonine.
Location(AA) Modifications Resource
38Phosphoserine (by GSK3) (By similarity).Swiss-Prot 53.0
42Phosphoserine (by GSK3) (By similarity).Swiss-Prot 53.0
46Phosphoserine (by PKA and ISPK) (Bysimilarity).Swiss-Prot 53.0
48Phosphoserine (RSK-1)Phospho.ELM 6.0
65Phosphoserine (by PKA) (By similarity).Swiss-Prot 53.0
65Phosphoserine (RSK-1)Phospho.ELM 6.0
759Phosphothreonine.Swiss-Prot 53.0
759PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
20N-linkedHMM predict
38Phosphoserine(ATM)HMM predict
38Phosphoserine(CDC2)HMM predict
46Phosphoserine(CK1)HMM predict
46Phosphoserine(CAMK2)HMM predict
46Phosphoserine(PKG)HMM predict
46Phosphoserine(CK2)HMM predict
46Phosphoserine(PKA)HMM predict
46Phosphoserine(PKB)HMM predict
48Phosphoserine(CK2)HMM predict
48PhosphoserineHMM predict
53SulfotyrosineHMM predict
53Phosphotyrosine(Syk)HMM predict
53Phosphotyrosine(Jak)HMM predict
53Phosphotyrosine(EGFR)HMM predict
65Phosphoserine(IKK)HMM predict
65Phosphoserine(CAMK2)HMM predict
65Phosphoserine(PKG)HMM predict
65Phosphoserine(PKC)HMM predict
65Phosphoserine(PKA)HMM predict
65Phosphoserine(PKB)HMM predict
135Phosphoserine(CK1)HMM predict
135Phosphoserine(IKK)HMM predict
223N-linkedHMM predict
226N-linkedHMM predict
261Phosphoserine(PKG)HMM predict
265Phosphoserine(CK1)HMM predict
266Phosphoserine(CK1)HMM predict
266Phosphoserine(CK2)HMM predict
269Phosphoserine(CK1)HMM predict
333Phosphothreonine(PKA)HMM predict
375Phosphoserine(MAPK)HMM predict
375Phosphoserine(ATM)HMM predict
375Phosphoserine(IKK)HMM predict
375Phosphoserine(CDC2)HMM predict
378Phosphoserine(CK2)HMM predict
405O-linkedHMM predict
422Phosphothreonine(CK2)HMM predict
423Phosphoserine(CK2)HMM predict
448N-linkedHMM predict
469AcetyllysineHMM predict
475AcetyllysineHMM predict
493Phosphothreonine(PKA)HMM predict
505Phosphoserine(CK2)HMM predict
506Phosphoserine(CK1)HMM predict
510Phosphotyrosine(Syk)HMM predict
511SulfotyrosineHMM predict
584Phosphoserine(CDC2)HMM predict
597Phosphothreonine(MAPK)HMM predict
668N-linkedHMM predict
671N-linkedHMM predict
698Phosphothreonine(CK2)HMM predict
735O-linkedHMM predict
736O-linkedHMM predict
739Phosphoserine(CK2)HMM predict
740Phosphothreonine(MAPK)HMM predict
740Phosphothreonine(CDC2)HMM predict
831Phosphothreonine(PKC)HMM predict
841N-linkedHMM predict
912N-linkedHMM predict
914Phosphoserine(CDC2)HMM predict
939O-linkedHMM predict
940PhosphothreonineHMM predict
943Phosphoserine(ATM)HMM predict
948Phosphothreonine(CK2)HMM predict
955N-linkedHMM predict
979O-linkedHMM predict
1002Phosphotyrosine(Jak)HMM predict
1002Phosphotyrosine(SRC)HMM predict
1039Phosphotyrosine(INSR)HMM predict
1048O-linkedHMM predict
1048Phosphoserine(IKK)HMM predict
1049Phosphoserine(IKK)HMM predict
1049Phosphoserine(CK1)HMM predict
1064N-linkedHMM predict
1069Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002711
  • Location:chr7 113301621-113346299
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 113364235 113364849 614 18243
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 113292530 113292568 38 9073
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 113320922 113320958 36 0
P300 T30-glioblastomaGSE21026 113319049 113319678 629 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018