AutismKB 2.0

Annotation Detail for PPP1R7


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Basic Information Top
Gene Symbol:PPP1R7 ( SDS22 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 7
Band: 2q37.3
Quick LinksEntrez ID:5510; OMIM: 602877; Uniprot ID:PP1R7_HUMAN; ENSEMBL ID: ENSG00000115685; HGNC ID: 9295
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
24Phosphoserine.
27Phosphoserine.
Location(AA) Modifications Resource
24Phosphoserine.Swiss-Prot 53.0
24PhosphoserinePhospho.ELM 6.0
27Phosphoserine.Swiss-Prot 53.0
27PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
27Phosphoserine(CK1)HMM predict
27Phosphoserine(CK2)HMM predict
128Phosphotyrosine(INSR)HMM predict
231N-linkedHMM predict
322Phosphoserine(PKG)HMM predict
360PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002712
  • Location:chr2 241738574-241771111
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 241737998 241738597 599 277
ETS1 JurkatGSE17954 241737173 241739059 1886 459
hScc1 BcellGSE12603 241737921 241738939 1018 145
p130 SenescentGSE19898 241738253 241738733 480 82
p130 shRbQuiescentGSE19898 241738272 241738731 459 73
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 241772904 241773130 226 1906
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 241750139 241750729 590 0
CTCF G2GSE9613 241756496 241756857 361 0
CTCF G2GSE9613 241768657 241768979 322 0
CTCF G2GSE9613 241769313 241771127 1814 0
H3ac HepG2E 241738913 241740181 1268 0
TFAP2C MCF7GSE21234 241761549 241761978 429 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
883 Unknown pSILAC let-7b PPP1R7 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000115685 n_a n_a n_a "epithelium, squamous cell, lymphocyte, macrophage, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15915 HTC PPP1R7 chr2 241809062 241842389 194 HTC PASK chr2 241765701 241809384Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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