AutismKB 2.0

Annotation Detail for PIWIL2


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Basic Information Top
Gene Symbol:PIWIL2 ( CT80,FLJ10351,HILI,MGC133049,PIWIL1L,mili )
Gene Full Name: piwi-like 2 (Drosophila)
Band: 8p21.3
Quick LinksEntrez ID:55124; OMIM: 610312; Uniprot ID:PIWL2_HUMAN; ENSEMBL ID: ENSG00000197181; HGNC ID: 17644
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
76Omega-N-methylarginine; by PRMT5;
76Symmetric dimethylarginine; by PRMT5;
97Omega-N-methylarginine; by PRMT5 (By
102Symmetric dimethylarginine; by PRMT5 (By
165Symmetric dimethylarginine; by PRMT5 (By
551Symmetric dimethylarginine; by PRMT5 (By
Location(AA) Modifications Resource
Location(AA) Modification Resource
47MethylarginineHMM predict
86Phosphothreonine(MAPK)HMM predict
86Phosphothreonine(CDK)HMM predict
97MethylarginineHMM predict
176Phosphothreonine(CDC2)HMM predict
178O-linkedHMM predict
185O-linkedHMM predict
186Phosphoserine(CDC2)HMM predict
186O-linkedHMM predict
193Phosphoserine(ATM)HMM predict
197Phosphoserine(CDC2)HMM predict
222Phosphothreonine(CDK)HMM predict
241Phosphotyrosine(Abl)HMM predict
270N-linkedHMM predict
297Phosphothreonine(CK2)HMM predict
344Phosphotyrosine(Syk)HMM predict
424N-linkedHMM predict
435N-linkedHMM predict
437Phosphothreonine(CDC2)HMM predict
524Phosphoserine(ATM)HMM predict
577N-linkedHMM predict
651Phosphothreonine(PKC)HMM predict
712Phosphoserine(CAMK2)HMM predict
747Phosphotyrosine(Syk)HMM predict
765N-linkedHMM predict
870O-linkedHMM predict
872Phosphothreonine(MAPK)HMM predict
916Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018068
  • Location:chr8 22188800-22269528
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb GrowingGSE19898 22177284 22177430 146 11444
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 22269559 22269852 293 177
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22188942 22189179 237 0
CTCF G2GSE9613 22200730 22201280 550 0
FOXA1 DLD1GSE12801 22265719 22266458 739 0
FOXA1 MCF7GSE15244 22265975 22266424 449 0
Fos K562GSE19551 22195865 22196305 440 0
P300 T30-glioblastomaGSE21026 22265715 22266921 1206 0
RARA MCF7GSE15244 22266004 22266711 707 0
TFAP2C MCF7GSE21234 22265880 22266646 766 0
hScc1 BcellGSE12603 22200730 22201128 398 0
hScc1 CdLSGSE12603 22200730 22201349 619 0
hScc1 G2GSE9613 22200730 22201383 653 0
p130 SenescentGSE19898 22266067 22266396 329 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018