AutismKB 2.0

Annotation Detail for SEC61A2


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Basic Information Top
Gene Symbol:SEC61A2 ( FLJ10578 )
Gene Full Name: Sec61 alpha 2 subunit (S. cerevisiae)
Band: 10p14
Quick LinksEntrez ID:55176; OMIM: NA; Uniprot ID:S61A2_HUMAN; ENSEMBL ID: ENSG00000065665; HGNC ID: 17702
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
45S-palmitoylHMM predict
46S-palmitoylHMM predict
56Phosphoserine(ATM)HMM predict
75Phosphothreonine(PKC)HMM predict
105Phosphothreonine(MAPK)HMM predict
197Phosphoserine(CDC2)HMM predict
199O-linkedHMM predict
346Phosphoserine(ATM)HMM predict
407Phosphothreonine(PKA)HMM predict
416Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018144
  • Location:chr10 12211703-12246831
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 HeLaGSE20725 12210865 12212152 1287 195
PHF8 Hs68minusFBSGSE20725 12211124 12211924 800 180
hScc1 BcellGSE12603 12211263 12211780 517 182
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Breast-CancerGSE22609 12232112 12232644 532 0
ER MCF7GSE19013 12232086 12232643 557 0
Oct1 HelaGSE14283 12233309 12233339 30 0
hScc1 CdLSGSE12603 12211232 12212727 1495 0
p63 keratinocytesGSE17611 12232103 12232551 448 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018