AutismKB 2.0

Annotation Detail for PPP2R1B


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Basic Information Top
Gene Symbol:PPP2R1B ( MGC26454,PP2A-Abeta,PR65B )
Gene Full Name: protein phosphatase 2, regulatory subunit A, beta
Band: 11q23.1
Quick LinksEntrez ID:5519; OMIM: 603113; Uniprot ID:2AAB_HUMAN; ENSEMBL ID: ENSG00000137713; HGNC ID: 9303
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
61Phosphoserine(IKK)HMM predict
72Phosphotyrosine(Syk)HMM predict
87N-linkedHMM predict
128Phosphoserine(ATM)HMM predict
132Phosphothreonine(MAPK)HMM predict
157Phosphothreonine(PKA)HMM predict
158O-linkedHMM predict
242Phosphoserine(IKK)HMM predict
248Phosphoserine(ATM)HMM predict
280Phosphoserine(CK1)HMM predict
589Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002716
  • Location:chr11 111113814-111142378
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 111142385 111142808 423 218
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 DLD1GSE12801 111123794 111124556 762 0
H3K4me3 colorectalcancer 111140743 111142169 1426 0
H3ac HepG2E 111140561 111143330 2769 0
Nanog hESGSE18292 111130205 111130378 173 0
Nanog hESGSE18292 111138889 111139364 475 0
Oct1 HelaGSE14283 111117074 111117102 28 0
PHF8 293TGSE20725 111141473 111142896 1423 0
hScc1 BcellGSE12603 111141558 111142766 1208 0
hScc1 G2GSE9613 111141345 111141937 592 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 21248297
hsa-let-7a hsa-let-7a-2 11 21248297
hsa-let-7a hsa-let-7a-3 22 21248297
hsa-let-7g hsa-let-7g 3 21248297
hsa-let-7g* hsa-let-7g 3 21248297
hsa-miR-134 hsa-mir-134 14 21248297
hsa-miR-145 hsa-mir-145 5 21248297
hsa-miR-145* hsa-mir-145 5 21248297
hsa-miR-155 hsa-mir-155 21 21248297
hsa-miR-155* hsa-mir-155 21 21248297
hsa-miR-200c hsa-mir-200c 12 21248297
hsa-miR-200c* hsa-mir-200c 12 21248297
hsa-miR-203 hsa-mir-203 14 21248297
hsa-miR-21 hsa-mir-21 17 21248297
hsa-miR-21* hsa-mir-21 17 21248297
hsa-miR-296-3p hsa-mir-296 20 21248297
hsa-miR-296-5p hsa-mir-296 20 21248297
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5183 mRNA SNF1LK2 chr11 110978431 111106788 146 mRNA PPP2R1B chr11 111102845 111142379Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018