Annotation Detail for ADI1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	ADI1 ( APL1,ARD,FLJ10913,MTCBP1,SIPL )
Gene Full Name:	acireductone dioxygenase 1
Band:	2p25.3
Quick Links	Entrez ID:55256; OMIM: 613400; Uniprot ID:MTND_HUMAN; ENSEMBL ID: ENSG00000182551; HGNC ID: 30576
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

No data

Location(AA)	Modification	Resource
46	Phosphotyrosine(Syk)	HMM predict
60	N-linked	HMM predict
61	Phosphotyrosine(SRC)	HMM predict
77	Phosphotyrosine(INSR)	HMM predict
141	N-linked	HMM predict
142	Phosphotyrosine(Syk)	HMM predict
176	Alanine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_018269
Location:chr2 3480697-3502305
strand:-

Upstream the gene:5 results
Downstream the gene:5 results
Inside the gene:13 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3K4me3	colorectal	cancer	3502761	3503255	494	703
H3ac	HepG2	E	3502587	3504052	1465	1014
Rb	Quiescent	GSE19898	3506211	3506383	172	3992
TAF	k562	GSE8489	3502761	3504052	1291	1101
p130	shRbQuiescent	GSE19898	3506110	3506564	454	4032

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	3471668	3471910	242	8909
CTCF	G2	GSE9613	3472527	3473273	746	7798
P300	T30-glioblastoma	GSE21026	3475581	3476452	871	4681
Rb	Quiescent	GSE19898	3476567	3476673	106	4078
hScc1	Bcell	GSE12603	3472821	3473212	391	7681

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	T30-glioblastoma	GSE21026	3501332	3502723	1391	0
CTCF	G2	GSE9613	3501635	3502515	880	0
ETS1	Jurkat	GSE17954	3500930	3503081	2151	0
FOXA1	MCF7	GSE15244	3487145	3487720	575	0
H3K4me3	colorectal	cancer	3500561	3501133	572	0
H3ac	HepG2	E	3500561	3501362	801	0
HIF1	Hypo	HepG2	3501298	3502314	1016	0
HIF1	Norm	HepG2	3501222	3502468	1246	0
Oct1	Hela	GSE14283	3495017	3495062	45	0
PHF8	293T	GSE20725	3501028	3503021	1993	0
PHF8	HeLa	GSE20725	3500996	3503013	2017	0
PHF8	Hs68plusFBS	GSE20725	3500827	3502776	1949	0
hScc1	Bcell	GSE12603	3501298	3501980	682	0

Validated miRNA targets

miR Walk:6 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-21	hsa-mir-21	17	21177307
hsa-miR-21	hsa-mir-21	17	20160498
hsa-miR-21*	hsa-mir-21	17	21177307
hsa-miR-21*	hsa-mir-21	17	20160498
hsa-miR-330-3p	hsa-mir-330	19	21177307
hsa-miR-330-5p	hsa-mir-330	19	21177307

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved