AutismKB 2.0

Annotation Detail for PPP2R5C


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Basic Information Top
Gene Symbol:PPP2R5C ( B56G,MGC23064,PR61G )
Gene Full Name: protein phosphatase 2, regulatory subunit B', gamma
Band: 14q32.31
Quick LinksEntrez ID:5527; OMIM: 601645; Uniprot ID:2A5G_HUMAN; ENSEMBL ID: ENSG00000078304; HGNC ID: 9311
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
348Phosphotyrosine.
349Phosphotyrosine.
354Phosphotyrosine.
422Nuclear localization signal (Potential).
497Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
92Phosphotyrosine(EGFR)HMM predict
92Phosphotyrosine(SRC)HMM predict
112N-linkedHMM predict
298Phosphoserine(IKK)HMM predict
383N-linkedHMM predict
451O-linkedHMM predict
497Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002719
  • Location:chr14 101345924-101463827
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 101481233 101481679 446 17629
P300 T30-glioblastomaGSE21026 101463815 101464330 515 245
Sox2 hESGSE18292 101481232 101481563 331 17570
USF1 HepG2E 101468800 101469042 242 5094
hScc1 BcellGSE12603 101468239 101468468 229 4526
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 101452185 101453371 1186 0
KLF4 hESGSE17917 101454475 101454886 411 0
Oct1 HelaGSE14283 101460197 101460226 29 0
hScc1 BcellGSE12603 101452847 101453304 457 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1084 Unknown pSILAC miR-16 PPP2R5C down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000078304 n_a n_a n_a "lymphocyte, lymphoblast" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma, non-Hodgkin's"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018